Fine needle aspiration cytology of pulmonary lesions: a reliable diagnostic test
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2004, Medical Clinics of North AmericaCitation Excerpt :The presence of bronchogenic carcinoma is established by radiographic imaging studies (eg, routine chest roentgenogram, thoracic axial CT scan, or MRI [67]) and the diagnosis is confirmed by histopathologic or cytopathologic examination of samples obtained by relevant sampling techniques, which are usually selected based on the site and accessibility of the lesion. These may include sputum cytology [68,69]; fiberoptic bronchoscopy with endobronchial or transbronchial biopsy; image-guided percutaneous fine-needle aspiration biopsy, yielding material for cytopathologic examination (with sensitivity as high as 92% and specificity up to 96%) [70]; mediastinoscopy; and pleural biopsy. In the presence of extrathoracic metastatic disease, these lesions (lymph node, liver, skin, bone marrow) are often biopsied, because the cell type of the lung cancer and inoperability of the primary lesion can be established by a single procedure.
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