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  • Clinical Oncology
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Randomized study of chemotherapy and surgery versus radiotherapy for stage IIIA non-small-cell lung cancer: a National Cancer Institute of Canada Clinical Trials Group Study

British Journal of Cancer volume 78, pages 683–685 (1998)Cite this article

Abstract

Thirty-one patients with stage IIIA (N2) non-small-cell lung cancer were randomized to receive radiotherapy alone or chemotherapy with cisplatin and vinblastine followed by surgery. Response rates to induction chemotherapy and radiotherapy were 50% and 53.3% respectively. Complete surgical resection was possible for 62.5% of patients. Median survival times were 16.2 and 18.7 months for radiotherapy alone and chemotherapy-surgery respectively (P = Ns), with no long-term improvement in survival seen with combined-modality treatment.

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Authors and Affiliations

  1. Interdepartmental Division of Oncology of the University of Toronto, Ontario, Canada

    FA Shepherd

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  1. FA Shepherd
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  2. MR Johnston
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  3. D Payne
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  4. R Burkes
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  5. J Deslauriers
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  7. LD de Bedoya
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  9. K James
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  10. B Zee
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Shepherd, F., Johnston, M., Payne, D. et al. Randomized study of chemotherapy and surgery versus radiotherapy for stage IIIA non-small-cell lung cancer: a National Cancer Institute of Canada Clinical Trials Group Study. Br J Cancer 78, 683–685 (1998). https://doi.org/10.1038/bjc.1998.560

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  • DOI: https://doi.org/10.1038/bjc.1998.560

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