Review ArticleStem cells and cell therapy approaches in lung biology and diseases
Abbreviations
AEC
alveolar epithelial cell
ALI
acute lung injury
ARDS
acute respiratory distress syndrome
BASC
bronchioalveolar stem cell
CCSP
Clara cell secretory protein
CF
cystic fibrosis
CFTR
cystic fibrosis transmembrane conductance regulator
CLP
cecal ligation and puncture
COPD
chronic obstructive pulmonary disease
eNOS
endothelial nitric oxide synthetase
EPC
endothelial progenitor cell
ESC
embryonic stem cell
FEV1
forced expiratory volume in 1 second
FVC
forced vital capacity
GFP
green fluorescent protein
HSC
hematopoietic stem cell
IPF
idiopathic pulmonary fibrosis
KGF
keratinocyte growth factor
LPS
lipopolysaccharide
MCT
monocrotaline
MHC
major histocompatibility complex
MSC
mesenchymal stromal (stem) cell
PH
pulmonary hypertension
pro-SPC
pro-surfactant protein C
Sca-1
stem cell antigen-1
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Supported by NHLBIHL087274 and HL081289 research grants from the Cystic Fibrosis Foundation and the American Lung Association and NCRR COBREP20 RR-155557.
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