Coronary artery diseaseImpact of Chronic Obstructive Pulmonary Disease on Post-Myocardial Infarction Outcomes
Section snippets
Study population
Data were collected from patients enrolled in a prospective, observational study of outcomes after MI between January 1, 2003 and June 28, 2004 at 19 centers across the United States (Appendix) for the Prospective Registry Evaluating Myocardial Infarction: Event and Recovery (PREMIER) study. Details of patient recruitment and enrollment have been previously described.10 In total, 2,498 patients provided informed consent and were enrolled. All patients were ≥18 years of age, had an increased
Results
Of 2,481 patients after MI, 387 (15.6%) had a history of COPD. Baseline sociodemographic, economic, co-morbid, disease severity, and treatment characteristics of those with and without COPD are presented in Table 1.
Discussion
We found that COPD was present in almost 1 of 6 patients with MI and was associated with important treatment differences, including fewer coronary revascularization procedures and less use of β blockers, aspirin, and cardiac rehabilitation. Our study is the first to provide insight into the role of COPD after MI in patients’ health status; notably, our data indicate that patients with COPD have worse quality of life and physical functioning and trend toward a greater prevalence of angina 1 year
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This project was principally supported by CV Therapeutics, Inc., Palo Alto, California.