Original ResearchGynecologyResponsiveness and minimally important difference of SF-6D and EQ-5D utility scores for the treatment of pelvic organ prolapse
Section snippets
Study design and participants
This study is a retrospective analysis that combined data from 4 large, U.S., multicenter POP surgical trials conducted by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)−sponsored Pelvic Floor Disorders Network (PFDN). The 4 trials were Outcomes following vaginal prolapse repair and mid urethral sling (OPUS),8 Operations and pelvic muscle training in the management of apical support loss (OPTIMAL),9 Colpopexy and Urinary Reduction Effort (CARE),10
Results
The methods and results of OPUS, OPTIMAL, CARE, and COLPO have been previously published.8, 9, 10, 11 These 4 studies enrolled a total of 1314 women (Table 1). The SF-6D was included in all 4 studies; the EQ-5D was included in CARE and COLPO. Women who had utility data at 12 months for the SF-6D (n = 1100) and EQ-5D (n = 715) were included in the current analysis. We included 410 of 466 women (88%) from OPUS, 309 of 374 (83%) from OPTIMAL, 284 of 322 (88%) from CARE and 118 of 152 (78%) from
Comment
This study shows that the SF-6D and EQ-5D have good validity properties and are responsive instruments for measuring the effect of reconstructive surgical treatment for POP. We observed moderate correlations of the SF-6D and EQ-5D scores with each other and condition-specific measures of POP symptoms and QOL, the PFDI and PFIQ, similar to other studies, demonstrating concurrent validity.7 For women undergoing reconstructive pelvic surgery for POP, scores for both instruments improved at 12
References (30)
EuroQol: the current state of play
Health Policy
(1996)- et al.
The estimation of a preference-based measure of health from the SF-36
J Health Econ
(2002) - et al.
Psychometric evaluation of 2 comprehensive condition-specific quality of life instruments for women with pelvic floor disorders
Am J Obstet Gynecol
(2001) - et al.
The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction
Am J Obstet Gynecol
(1996) - et al.
The COSMIN study reached international consensus on taxonomy, terminology, and definitions of measurement properties for health-related patient-reported outcomes
J Clin Epidemiol
(2010) - et al.
Defining clinically meaningful change in health- related quality of life
J Clin Epidemiol
(2003) - et al.
Recommended methods for determining responsiveness and minimally important differences for patient-reported outcomes
J Clin Epidemiol
(2008) - et al.
Methods to explain the clinical significance of health status measures
Mayo Clin Proc
(2002) - et al.
Shifts in national rates of inpatient prolapse surgery emphasize current coding inadequacies
Female Pelvic Med Reconstr Surg
(2011) Practice bulletin no. 185: Pelvic organ prolapse
Obstet Gynecol
(2017)
Methods for the economic evaluation of health care programmes
Quality-adjusted life years, utility theory, and healthy-years equivalents
Med Decis Mak
Validity of utility measures for women with pelvic organ prolapse
Am J Obstet Gynecol
A midurethral sling to reduce incontinence after vaginal prolapse repair
N Engl J Med
Comparison of 2 transvaginal surgical approaches and perioperative behavioral therapy for apical vaginal prolapse: the OPTIMAL randomized trial
JAMA
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M.D.B reports Royalties from Elsevier, UpToDate; H.E.R. reports the following: Pelvalon, Consultant and grant support, Renovia, Consultant; Royalties from UptoDate; Travel funds IUGA; and Travel funds, ICS; NICHD, NIA, PCORI. A.G. reports Ninomed stock ownership. J.P.S. reports research support from Site PI for Myrbetriq trial supported by Astellas. R.G.R is DSMB chair for the TRANSFORM trial sponsored by American Medical Systems, and reports Stipend and travel from ABOG and IUGA and Royalties from Uptodate. The other authors report no conflict of interest.
Financial support for this project was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development and the National Institutes of Health Office of Research on Women’s Health (5U24HD069031-07).
Cite this article as: Harvie HS, Honeycutt AA, Neuwahl SJ, et al. Responsiveness and minimally important difference of SF-6D and EQ-5D utility scores for the treatment of pelvic organ prolapse. Am J Obstet Gynecol 2019;220:265.e1-11.