ResearchObstetricsSelf-reported short sleep duration and frequent snoring in pregnancy: impact on glucose metabolism
Section snippets
Materials and Methods
This study was a planned secondary analysis of data from a prospective, observational study designed to evaluate the prevalence of and trends in sleep disturbances across pregnancy.25 The study was approved by the institutional review board of Northwestern University, Chicago, IL. Patients were recruited in the outpatient setting from among women who received care at Northwestern Memorial Hospital affiliated practices. These practices serve women who have both government-based and private
Results
Of the 224 eligible women who were approached, 202 (90%) agreed to participate and completed the baseline survey. In all, 189 of these women participated in the third-trimester survey as well. The mean gestational age was 13.8 ± 3.8 and 30.0 ± 2.2 weeks at the first and second survey, respectively. Demographic characteristics of the study population, as a whole, and stratified by sleep complaints, are provided in Table 1. Results of 1-hour OGT screening were available for 182 women. For 6 women
Comment
This study examined glucose metabolism and risk of GDM in healthy nulliparous women reporting SSD and FS during pregnancy. Our findings suggest that women with these sleep disturbances are at increased risk of impaired glucose tolerance and GDM. Studies of nonpregnant individuals have linked SSD and SDB to fasting hyperglycemia, impaired glucose tolerance, and type 2 diabetes.14, 15, 16, 17, 18, 19, 20, 21 Yet, evidence for the association between sleep and pregnancy abnormalities has been
References (36)
- et al.
Sleep disturbances and chronic disease in older adults: results of the 2003 National Sleep Foundation Sleep in America survey
J Psychosom Res
(2004) - et al.
The metabolic consequences of sleep deprivation
Sleep Med Rev
(2007) - et al.
Epidemiology, risk factors, and consequences of obstructive sleep apnea and short sleep duration
Prog Cardiovasc Dis
(2009) - et al.
Sleep duration as a risk factor for incident type 2 diabetes in a multiethnic cohort
Ann Epidemiol
(2009) - et al.
Can history and physical examination reliably diagnose pediatric obstructive sleep apnea/hypopnea syndrome?A systematic review of the literature
Otolaryngol Head Neck Surg
(2004) - et al.
Impact of sleep debt on metabolic and endocrine function
Lancet
(1999) - et al.
Effects of pregnancy on mothers' sleep
Sleep Med
(2002) - et al.
Sleep disturbances during pregnancy
J Obstet Gynecol Neonatal Nurs
(2000) - et al.
Inflammation, oxidative stress, and the vascular endothelium in obstructive sleep apnea
Trends Cardiovasc Med
(2008) - et al.
Cardiovascular, inflammatory, and metabolic consequences of sleep deprivation
Prog Cardiovasc Dis
(2009)
Sleep and health: everywhere and in both directions
Arch Intern Med
A prospective study of self-reported sleep duration and incident diabetes in women
Diabetes Care
Role of sleep duration and quality in the risk and severity of type 2 diabetes mellitus
Arch Intern Med
Sleep-disordered breathing, glucose intolerance, and insulin resistance: the sleep heart health study
Am J Epidemiol
Sleep duration in the United States: a cross-sectional population-based study
Am J Epidemiol
Epidemiology of obstructive sleep apnea: a population health perspective
Am J Respir Crit Care Med
Assessment of the validity and utility of a sleep-symptom questionnaire
Am J Respir Crit Care Med
Identification of obstructive sleep apnea in patients who snore
Laryngoscope
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2022, American Journal of Obstetrics and GynecologyThe effect of sleep impairment on gestational diabetes mellitus: a systematic review and meta-analysis of cohort studies
2020, Sleep MedicineCitation Excerpt :Pooled results indicated that pregnant women with poor sleep quality were more likely to suffer from GDM, with little heterogeneity (RR with 95% CI = 1.26 [1.11, 1.44], I2 = 0.00%, P-heterogeneity = 0.52) (Fig. 2). Seven studies (8,291 pregnant women with 1,085 GDM cases) investigated the relationship between snoring and the risk of GDM [31,36,37,49–52]. A detrimental effect of snoring on the risk of GDM was found, with high heterogeneity (RR with 95% CI = 1.45 [1.12, 1.87], I2 = 50.10%, P-heterogeneity = 0.06) (Fig. 2).
Supported in part by research Grant 1K12HD050121 from the National Institutes of Health, National Institute of Child Health and Human Development.
Cite this article as: Facco FL, Grobman WA, Kramer J, et al. Self-reported short sleep duration and frequent snoring in pregnancy: impact on glucose metabolism. Am J Obstet Gynecol 2010;203:142.e1-5.