Trends in Microbiology
OpinionViral potentiation of bacterial superinfection of the respiratory tract
References (30)
J. Pediatr. (St Louis)
(1992)Immunol. Allergy Clin. North Am.
(1994)J. Allergy Clin. Immunol.
(1992)J. Allergy Clin. Immunol.
(1992)Int. J. Pediatr. Otorhinolaryngol.
(1992)- et al.
J. Pediatr. (St Louis)
(1990) Pediatrics
(1990)- et al.
J. Laryngol. Otol.
(1991)- et al.
Pediatr. Infect. Dis. J.
(1994)
Ear Nose Throat J.
Acta Pediatr. Scand.
Acta Pediatr.
Acta Pediatr.
Pediatr. Infect. Dis. J.
Cited by (113)
Outcome of Respiratory Viral Infections in Hematopoietic Stem Cell Transplant Recipients
2024, Transplantation ProceedingsThe contribution of the immune response to enhanced colibacillosis upon preceding viral respiratory infection in broiler chicken in a dual infection model
2021, Veterinary Immunology and ImmunopathologyCitation Excerpt :These events were first explained by virus-induced mechanical damage to the mucocilliary respiratory tissue, which was thought to hamper proper bacterial clearance (Kotani et al., 1987; Bakaletz, 1995). In addition, virus-induced increase of bacterial attachment factors was found to aid bacterial manifestation in the upper respiratory tract (Bakaletz, 1995; McCullers and Rehg, 2002). Alternatively, primary viral airway infection is known to facilitate secondary bacterial infection via cell-mediated immune pathways, as was clearly demonstrated in studies on influenza virus-predisposed streptococcal lung infection in mice (reviewed by Robinson et al. (2015) and Rynda-Apple et al. (2015)).
Recent approaches for control of E. coli and respiratory complex in Middle East
2018, Saudi Journal of Biological SciencesCitation Excerpt :Three possible causes have been described as mechanisms for functional damage. Viral replication in the upper respiratory tract causes loss of cilia and ciliated cells (Bakaletz, 1995), decreased ciliary activity impairs mucociliary clearance (Wilson et al., 1996) and finally, damage to epithelium may provide more attachment sites for bacteria (El Ahmer et al., 1999). A second set of hypotheses suggests altered innate immune responses.
Viruses: Bystanders of periodontal disease
2017, Microbial PathogenesisFactors influencing the development of otitis media among Sicilian children affected by upper respiratory tract infections
2016, Brazilian Journal of OtorhinolaryngologyCitation Excerpt :Thus middle ear is an anatomical extension of the airway by way of the Eustachian tube and, as hypothesized by Nguyen et al., is considered a component of the “united airway concept”.8 Viral URTI leads to Eustachian tube inflammation resulting in its dysfunction and negative middle ear pressure permitting secretions containing the infecting virus and pathogenic bacteria that colonize the nasopharynx to enter the middle ear.9 Environmental, epidemiologic and familial risk factors for OM (such as sex, socioeconomic and educational factors, smoke exposure, allergy or duration of breastfeeding) have been previously reported,2–5,8,10,11 but actually no data about their diffusion among Sicilian children with URTIs are available; thus, because of the high prevalence (14.43%) of OM in Sicilian children affected by URTIs,4 we examined the main OM risk factors, either separately or in combination, to provide additional data about their impact in the pathogenesis of OM.