IgA subclasses in sputum from patients with bronchiectasis
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Cited by (7)
The role of tracheobronchial mucus in drug administration to the airways
1993, Advanced Drug Delivery ReviewsImmunity and bacterial colonisation in bronchiectasis
2012, ThoraxCitation Excerpt :Stability of IgA2 is maintained better than IgA1 in the presence of infection because of resistance to IgA proteases produced by many pathogenic bacteria.9 There is increased production of IgA2 in the presence of infection indicated by an increase in the proportion of IgA2 with increasing sputum purulence.10 IgA in airway secretions binds to lectin-like bacterial adhesins blocking epithelial colonisation and operating as a generic immune barrier.
Reduced epithelial expression of secretory component in small airways correlates with airflow obstruction in chronic obstructive pulmonary disease
2001, American Journal of Respiratory and Critical Care MedicineCorrelation between IgA antibody and eosinophil cationic protein levels in induced sputum from asthmatic patients
1997, Clinical and Experimental Allergy
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