Elsevier

The Lancet

Volume 345, Issue 8953, 1 April 1995, Pages 831-832
The Lancet

Sleep pattern and supplementary oxygen requirements in infants with chronic neonatal lung disease

https://doi.org/10.1016/S0140-6736(95)92966-5Get rights and content

Abstract

Seven infants with chronic neonatal lung disease and baseline oxygen saturation greater than 90% were studied with overnight polysomnography in their prescribed oxygen environment, and on a second night with 0·25 L/min additional oxygen. All had sleep fragmentation and decreased rapid-eye-movement (REM) sleep, which was reversed after the increased oxygen. Sleep duration (p<0·003), percentage REM sleep (p<0·001), and mean REM sleep period length (p<0·001) were increased, and arousals in REM sleep decreased (p<0·05), with improved oxygenation. We conclude that, in infants with chronic neonatal lung disease, arousal mechanisms minimise oxygen desaturation but induce sleep disruption.

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