Elsevier

The Lancet

Volume 356, Issue 9241, 4 November 2000, Pages 1573-1574
The Lancet

Research Letters
Dietary vitamin E, IgE concentrations, and atopy

https://doi.org/10.1016/S0140-6736(00)03132-9Get rights and content

Summary

Vitamin E inhibits IgE responses to allergic stimuli in animals. We investigated the relation between dietary vitamin E intake and serum IgE concentrations and atopy, measured as allergen skin sensitisation, in a random sample of 2633 adults. Higher concentrations of vitamin E intake were associated with lower serum IgE concentrations and a lower frequency of allergen sensitisation. These findings may explain the beneficial effect of dietary vitamin E on the incidence of asthma.

References (5)

There are more references available in the full text version of this article.

Cited by (148)

  • Therapeutic potential of palm oil vitamin E-derived tocotrienols in inflammation and chronic diseases: Evidence from preclinical and clinical studies

    2022, Food Research International
    Citation Excerpt :

    Asthma patients were discovered to have lower vitamin E levels in their airways, which suggests this antioxidant may be beneficial in the treatment of asthma (Abdala-Valencia et al., 2013; Pearson et al., 2004). Numerous studies appear to support the use of T3s in the therapy of asthma (Cook-Mills et al., 2016; Fogarty et al., 2000; Peh et al., 2015). High intakes of TRF or T3 isoforms, for example, have been shown to improve asthma symptoms (Harada et al., 2015; Qu et al., 2017; Zainal et al., 2019a).

  • Anti-allergic effects of vitamin E in allergic diseases: An updated review

    2021, International Immunopharmacology
    Citation Excerpt :

    and 1–10% respectively [73,74]. Vitamin E can be effective in the treatment of AD due to its strong antioxidant properties and the ability to reduce the serum level of IgE antibody [75]. It has been indicated that the serum level of α-tocopherol is negatively associated with the prevalence of AD [76].

  • Micronutrients in skin immunity and associated diseases

    2017, Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support
  • Asthma in Older Children: Special Considerations

    2016, Pediatric Allergy: Principles and Practice: Third Edition
  • Dietary lipid determines the health of airway epithelia and the lungs

    2016, Handbook of Lipids in Human Function: Fatty Acids
View all citing articles on Scopus
View full text