Clinical study
Sarcoidosis mortality in the United States, 1979–1991: An analysis of multiple-cause mortality data

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Purpose

We sought to describe sarcoidosis mortality in the United States from 1979 through 1991.

Methods

We analyzed death certificate reports compiled by the National Center for Health Statistics for the period 1979 through 1991.

Results

Of the 26,866,600 people who died during the study period, 9,014 had a diagnosis of sarcoidosis listed on their death certificates. We restricted our study group to 5,791 people who died because of sarcoidosis or one of its complications. Among men, age-adjusted mortality rates increased from 1.3 per 1,000,000 in 1979 to 1.6 per 1,000,000 in 1991, and among women, these rates increased from 1.9 per 1,000,000 in 1979 to 2.5 per 1,000,000 in 1991. Age-adjusted mortality rates were consistently higher among blacks than among whites. Age-adjusted mortality rates, stratified by race, varied by state. Among whites, the highest rates were in northern states, while among blacks, the highest rates were in the Middle Atlantic and northern Midwestern states.

Conclusions

Reported mortality due to sarcoidosis varies by region, sex, and race. We cannot determine whether these differences are related to characteristics of the disease, or problems in death certification and coding.

References (21)

  • DeRemeeRA

    Sarcoidosis

  • BresnitzEA et al.

    Epidemiology of sarcoidosis

    Epidemiol Rev

    (1983)
  • ThomasPD et al.

    Current concepts of the pathogenesis of sarcoidosis

    Am Rev Respir Dis

    (1987)
  • IwaiK et al.

    Pathological studies on sarcoidosis autopsy. 1 Epidemiological features of 320 cases in Japan

    Acta Pathol Japan

    (1993)
  • TeirsteinAS et al.

    Worldwide distribution and epidemiology of sarcoidosis

  • YoungRC et al.

    Epidemiology of sarcoidosis: ethnic and geographic considerations

    JNMA

    (1974)
  • JamesPG et al.

    A worldwide review of sarcoidosis Proceedings of the VIIth International Conference on Sarcoidosis and Other Granulomatous Disorders

    Ann NY Acad Sci

    (1976)
  • LongcopeWT et al.

    A study of sarcoidosis Based on a combined investigation of 160 cases including 30 autopsies from the Johns Hopkins Hospital and Massachusetts General Hospital

    Medicine

    (1952)
  • U.S. Public Health Service

    international Classification of Diseases

    (1980)
  • Centers for Disease Control Prevention

    Advance report of final mortality statistics, 1991

There are more references available in the full text version of this article.

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