Originial articleTumour necrosis factor and cachexia: a current perspective
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2017, Experimental GerontologyCitation Excerpt :In the assessment of whether long-term resistance and endurance training affect the blood lipid components, including adipocytokines, we found that no parameters changed (Table 4). TNF-α is considered a pro-inflammatory cytokine that contributes to breakdown and wasting of skeletal muscle, and it is associated with age-related inflammatory diseases such as rheumatoid arthritis, dementia, cardiovascular disease, and type 2 diabetes (Espat et al., 1994; Visser et al., 2002). In one study, TNF-α decreased by 16% after a 3-month resistance training intervention (Onambele-Pearson et al., 2010).
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