ORIGINAL ARTICLESEridothelin immunoreactivity of airway epithelium in asthmatic patients
References (31)
- et al.
Cloning and sequence analysis of cDNA encoding the precursor of a human endothelin-derived vascoconstrictor peptide, endothelin: identity of human and porcine endothelin
FEBS Lett
(1988) - et al.
Endothelin stimulates c-fos and c-myc expression and proliferation of vascular smooth muscle cells (letter)
FEBS Lett
(1988) - et al.
Endothelin-mediated stimulation of DNA synthesis in vascular smooth muscle cells
Biochem Biophys Res Commun
(1989) - et al.
A novel vasoactive peptide endothelin stimulates mitogenesis through inositol lipid turnover in Swiss 3T3 fibroblasts
J Biol Chem
(1989) - et al.
Pharmacological modulation of the bronchopulmonary action of the vasoactive peptide, endothelin, administered by aerosol in the guinea-pig
Biochem Biophys Res Commun
(1989) - et al.
Formation of endothelin by cultured airway epithelial cells
FEBS Lett
(1989) - et al.
Standardization of bronchial inhalation challenge procedures
J Allergy Clin Immunol
(1975) - et al.
Subepithelial fibrosis in the bronchi of asthmatics
Lancet
(1989) - et al.
Endothelin and bronchial asthma
Lancet
(1989) - et al.
Endothelin-1 stimulates arachidonate 15-lipoxygenase activity and oxygen radical formation in the rat distal lung
Biochem Biophys Res Commun
(1990)
The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes
Proc Natl Acad Sci USA
A novel potent vasoconstrictor peptide produced by vascular endothelial cells
Nature
Analysis of endothelin-1-induced contractions of guinea-pig trachea, pulmonary veins and different types of pulmonary arteries
Acta Physiol Scand
Occurrence and effects of endothelin in guinea-pig cardiopulmonary tissue
Acta Physiol Scand
Endothelin-induced contractions of tracheal smooth muscle and identification of specific endothelin binding sites in the trachea of the rat
Br J Pharmacol
Cited by (255)
Angiogenesis and remodelling in asthma
2009, Revue Francaise d'AllergologieAirway remodeling
2009, Asthma and COPDAirway remodeling
2008, Asthma and COPD: Basic Mechanisms and Clinical ManagementEndothelin-1 in exhaled breath condensate of stable and unstable asthma patients
2008, Respiratory MedicineCitation Excerpt :There have been numerous studies investigating whether differences exist between asthmatics and non-asthmatic volunteers, especially with regard to the expression of ET-1 by cultured airway epithelial cells, as well as the levels of ET-1 in saliva, sputum, plasma, BAL fluid, and bronchial biopsy specimens.11–13 Furthermore, the relationship between levels of ET-1 and markers of airway inflammation and bronchial reactivity has also been the object of several studies.4,14,15 The influence of anti-inflammatory therapy on levels of ET-1 has been investigated as well.16–18
The allergic cascade: Review of the most important molecules in the asthmatic lung
2007, Immunology LettersCitation Excerpt :There are a number of potential sources of ET-1 within the airways, including BECs, vascular endothelial cells, macrophages and mast cells [151]. Increased levels of ET-1 were found in BAL fluid from asthmatics [126] and immunoreactivity for ET-1 is raised in the epithelium of asthmatic subjects [152]. Vascular endothelial growth factor (VEGF) may contribute to the pathophysiology of asthma in several ways.
Endothelin In The Airways
2006, Handbook of Biologically Active Peptides