MEDICAL SCIENCEHypothesis: exercise-induced asthma as a vascular phenomenon
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Cited by (155)
Anti-muscarinic drugs as preventive treatment of exercise-induced bronchoconstriction (EIB) in children and adults
2020, Respiratory MedicineCitation Excerpt :Well-designed studies performed by Anderson and co-workers showed that the respiratory water loss and the increase in osmolarity of the airways surface liquid represent major determinants of EIB (osmotic theory) [22]. The vasodilation associated with airways rewarming (thermal theory) has also been reported to play a key-role in inducing bronchial obstruction after exercise [23]. Furthermore, a direct effect on the bronchial epithelium caused by viral infections, occupational agents and exercise itself may represent an alternative mechanism of EIB [24].
The Future of Exertional Respiratory Problems: What Do We Know About the Total Airway Approach and What Do We Need to Know?
2018, Immunology and Allergy Clinics of North AmericaCitation Excerpt :Bonini and Silvers (see Matteo Bonini and William Silvers’ article, “Exercise-Induced Bronchoconstriction: Background, Prevalence and Sport Considerations,” in this issue) discuss the effect of different sports on the prevalence of these conditions.21 Kippelen and colleagues (see Pascale Kippelen and colleagues’ article, “Mechanisms and Biomarkers of Exercise-Induced Bronchoconstriction,” in this issue) synthesize an incredible review of decades of mechanistic research in EIB, incorporating observations attributable to vascular phenomena into the now accepted osmotic hypothesis.22,23 In addition to cellular mechanisms, newer neurogenic mechanisms of disease are discussed.
Exercise-Induced Bronchoconstriction: Background, Prevalence, and Sport Considerations
2018, Immunology and Allergy Clinics of North AmericaDynamic hyperinflation in patients with asthma and exercise-induced bronchoconstriction
2017, Annals of Allergy, Asthma and ImmunologySport, asthma and allergy
2017, Revue Francaise d'AllergologieMeteorological conditions, climate change, new emerging factors, and asthma and related allergic disorders. A statement of the World Allergy Organization
2015, World Allergy Organization Journal