A sigmold model of the static volume-pressure curve of human lung

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Abstract

The authors present a sigmoid mathematical model of the pressure-volume curve of the human lung, based on a relationship between the specific compliance and the maximal pulmonary volume: dVV·dPK′ = VoVVo This model fits better the experimental data obtained in 20 young normal adults than the currently used exponential model of Salazar and Knowles (1964). The independence between the constant K' and body height is interpreted as a constancy of pulmonary structure for normal subjects of the same age range. Human lung Lung compliance Mechanics of breathing Specific compliance Volume-pressure curve of lung

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Work partially realized with the financial aid of the Commission of the E.E.C. (Luxemburg) and under contract of the‘Ministére de la Politique Scientifique’ in the framework of the Association Euratom-Université de Pisè-Université de Bruxelles.

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