Iron mobilization from asbestos by chelators and ascorbic acid
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Mechanisms and shapes of causal exposure-response functions for asbestos in mesotheliomas and lung cancers
2023, Environmental ResearchIron removal from raw asbestos by siderophores-producing Pseudomonas
2020, Journal of Hazardous MaterialsCitation Excerpt :Few siderophores demonstrated their ability to release iron from asbestos fibers. Indeed, iron removal by desferrioxamine siderophore evidenced from raw asbestos, on chrysotile fibers (Lund and Aust, 1990) and amphibole fibers such as crocidolite and amosite (Chao and Aust, 1994). Siderophore-producing Pseudomonas are widespread bacteria in soil and known for mineral-weathering capacity.
Iron from a geochemical viewpoint. Understanding toxicity/pathogenicity mechanisms in iron-bearing minerals with a special attention to mineral fibers
2019, Free Radical Biology and MedicineCitation Excerpt :The mobilization rate of iron by ferrozine was similar when compared by exposed surface, but was higher from crocidolite than from amosite when the comparison was given on a weight basis [96]. Little amount of iron was released from chrysotile in presence of ferrozine [96,97] and from tremolite treated with desferoxamine [98], because of their low iron content. Other factors affecting ion mobilization include type of chelator, iron oxidation state and pH of the reaction medium [74].
New insights into the toxicity of mineral fibres: A combined in situ synchrotron μ-XRD and HR-TEM study of chrysotile, crocidolite, and erionite fibres found in the tissues of Sprague-Dawley rats
2017, Toxicology LettersCitation Excerpt :The TEM study of Gronow (1987) showed that crocidolite fibres which had undergone 1024 h dissolution in water at neutral pH produced no evidence of changes at the surface of the minerals and there was no reduction in the intensity of diffraction patterns from bundles of parallel fibres. The picture does not change for crocidolite in the tissues, although the action of Fe chelators present in physiological fluids should more efficiently prompt extraction of Fe from the fibre surfaces (Lund and Aust, 1990; Werner et al., 1995). Although crocidolite in the tissues is virtually stable except for a very thin silica rich dissolution halo in the time span of the experiments, slight intra-structure modifications do occur.
Multiple aspects of the interaction of biomacromolecules with inorganic surfaces
2011, Advanced Drug Delivery ReviewsCitation Excerpt :Similar reactivity toward DNA was observed in pyrite [223]. Alternatively oxidative stress may derive from metals leached from the surface by endogenous chelators [228]. Semiconducting materials are intrinsically able to exchange electrons with molecular entities which come into contact with the surface, if activated by light or heat.
Chemical characterisation and cytotoxic effects in A549 cells of urban-air PM10 collected in Torino, Italy
2010, Environmental Toxicology and Pharmacology