Clinical studyRaynaud's phenomenon of the lung☆
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Cited by (71)
Part II: The treatment of primary and secondary Raynaud's phenomenon
2024, Journal of the American Academy of DermatologyPart I: Epidemiology, pathophysiology, and clinical considerations of primary and secondary Raynaud's phenomenon
2024, Journal of the American Academy of DermatologyUndifferentiated Connective Tissue Disease at risk for systemic sclerosis (SSc) (so far referred to as very early/early SSc or pre-SSc)
2015, Autoimmunity ReviewsCitation Excerpt :Nevertheless, the evidence emerged from studies involving both early SSc and UCTD patients might challenge this position [31]. Actually, the 3 preclinical alterations detected by us with a similar prevalence in early SSc and UCTD patients likely depend on vascular disease: DLCO is affected by perfusion [32] and decreases under cold stress both in patients with secondary and primary RP [33]; a reduced basal pressure of the low esophageal sphincter, which reflects neural dysfunction, is thought to depend on vascular disease [34] and a decreased esophageal blood flow has been reported in patients with RP [35]; an inverted E/A ratio reflecting diastolic dysfunction, could depend on either myocardial ischemia or myocardial fibrosis [36] and an acute diastolic dysfunction has been reported in a primary RP patient following a coronary vasospasm [37]. Furthermore, RP-associated UCTD patients, unlike subjects with primary Raynaud disease and similarly to those with SSc, present an impaired endothelium dependent vasodilation [38] and can develop digital ulcers [39].
Systemic Sclerodermas
2015, Textbook of Pediatric RheumatologyThe systemic sclerodermas and related disorders
2011, Textbook of Pediatric RheumatologyPulmonary vascular manifestations of mixed connective tissue disease
2005, Rheumatic Disease Clinics of North America
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This work was supported in part by National Institutes of Health Grants HL-16784 and HL-07216.
- 1
From the Departments of Medicine and Surgery, University of Rochester School of Medicine, Rochester, New York.
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Current address: Pulmonary Division, Loyola University of Chicago, Stritch School of Medicine, 2160 South First Avenue, Maywood, Illinois 60153.