Case report
Silo filler's disease: Clinical, physiologic and pathologic study of a patient

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Abstract

A case of silo filler's disease is reported, resulting from exposure to silage six weeks after it was stored. Pulmonary function studies and lung biopsy specimens were obtained in the acute stage and during the period of convalescence. Pulmonary function studies showed the acute disturbance to be one of impaired diffusion of oxygen across the alveolar-capillary membrane. The initial lung biopsy showed a bronchiolitis. Following therapy with corticosteroids the alveolar diffusion capacity became normal, but the pulmonary function studies as well as the biopsy indicated that a mild degree of pulmonary hyperinflation resulted.

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  • Cited by (0)

    This study was supported in part by the U. S. Public Health Service Grant B 1594 (C3) and the U. S. Public Health Service Training Grant H 5485.

    Present address: 185 Lexington Avenue, Passaic, New Jersey.

    1

    From the Departments of Medicine and Pathology, State University of New York, Downstate Medical Center, and the Kings County Hospital Center, Brooklyn, New York.

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