Regular ArticlesREGULATION OF HUMAN EOTAXIN-3/CCL26 EXPRESSION: MODULATION BY CYTOKINES AND GLUCOCORTICOIDS
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2021, CytokineCitation Excerpt :CCL26 is a chemokine that belongs to the eotaxin family (eotaxin-1/CCL11, eotaxin-2/CCL24, and eotaxin-3/CCL26) [114]. Eotaxins are released by epithelial, mesenchymal, and endothelial cells in response to various mediators, including IL-4, IL-13, and TNF-α [115–117]. Eotaxins are potent chemoattractants for eosinophils [115,117], which play a central role in type-2 immunity such as host defense against parasitic helminth infections, tissue repair and remodeling, and allergic diseases [118,119].
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- f1
Correspondence to: Miles Banwell, Leukocyte Biology Section, Biomedical Sciences Division, Imperial College School of Medicine, South Kensington, London SW7 2AZ, UK. E-mail: [email protected]
- f2
Present address: T. J. Mitchell's, Skin Tumour Unit, St. Johns Institute of Dermatology, St. Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK