Asthma Mechanisms

Phosphoinositide 3-kinase-δ regulates fungus-induced allergic lung inflammation through endoplasmic reticulum stress
Kyung Sun Lee, Jae Seok Jeong, So Ri Kim, Seong Ho Cho, Narasaiah Kolliputi, Yun Hee Ko, Kyung Bae Lee, Suk Chul Park, Hae Jin Park, Yong Chul Lee

Thorax Jan 2016, 71 (1) 52-63; DOI: 10.1136/thoraxjnl-2015-207096
Greater parallel heterogeneity of airway narrowing and airway closure in asthma measured by high-resolution CT
J R Dame Carroll, J S Magnussen, N Berend, C M Salome, G G King

Thorax Dec 2015, 70 (12) 1163-1170; DOI: 10.1136/thoraxjnl-2014-206387
Pulmonary macrophages: key players in the innate defence of the airways
Adam J Byrne, Sara A Mathie, Lisa G Gregory, Clare M Lloyd

Thorax Dec 2015, 70 (12) 1189-1196; DOI: 10.1136/thoraxjnl-2015-207020
Persistence of asthma following allergen avoidance is associated with proTh2 myeloid dendritic cell activation
Antoine Froidure, Olivier Vandenplas, Vinciane D'Alpaos, Geneviève Evrard, Charles Pilette

Thorax Oct 2015, 70 (10) 967-973; DOI: 10.1136/thoraxjnl-2014-206364
The Canadian Healthy Infant Longitudinal Development (CHILD) Study: examining developmental origins of allergy and asthma
Padmaja Subbarao, Sonia S Anand, Allan B Becker, A Dean Befus, Michael Brauer, Jeffrey R Brook, Judah A Denburg, Kent T HayGlass, Michael S Kobor, Tobias R Kollmann, Anita L Kozyrskyj, W Y Wendy Lou, Piushkumar J Mandhane, Gregory E Miller, Theo J Moraes, Peter D Pare, James A Scott, Tim K Takaro, Stuart E Turvey, Joanne M Duncan, Diana L Lefebvre, Malcolm R Sears, the CHILD Study investigators

Thorax Oct 2015, 70 (10) 998-1000; DOI: 10.1136/thoraxjnl-2015-207246
Microfibrillar-associated protein 4 modulates airway smooth muscle cell phenotype in experimental asthma
Bartosz Pilecki, Anders Schlosser, Helle Wulf-Johansson, Thomas Trian, Jesper B Moeller, Niels Marcussen, Juan A Aguilar-Pimentel, Martin Hrabe de Angelis, Jorgen Vestbo, Patrick Berger, Uffe Holmskov, Grith L Sorensen

Thorax Sep 2015, 70 (9) 862-872; DOI: 10.1136/thoraxjnl-2014-206609
Anti-inflammatory effects of PGE₂ in the lung: role of the EP₄ receptor subtype
Mark A Birrell, Sarah A Maher, Bilel Dekkak, Victoria Jones, Sissie Wong, Peter Brook, Maria G Belvisi

Thorax Aug 2015, 70 (8) 740-747; DOI: 10.1136/thoraxjnl-2014-206592
Lebrikizumab in moderate-to-severe asthma: pooled data from two randomised placebo-controlled studies
Nicola A Hanania, Michael Noonan, Jonathan Corren, Phillip Korenblat, Yanan Zheng, Saloumeh K Fischer, Melissa Cheu, Wendy S Putnam, Elaine Murray, Heleen Scheerens, Cecile TJ Holweg, Romeo Maciuca, Sarah Gray, Ramona Doyle, Dana McClintock, Julie Olsson, John G Matthews, Karl Yen

Thorax Aug 2015, 70 (8) 748-756; DOI: 10.1136/thoraxjnl-2014-206719
Effect of bariatric surgery on asthma control, lung function and bronchial and systemic inflammation in morbidly obese subjects with asthma
Astrid van Huisstede, Arjan Rudolphus, Manuel Castro Cabezas, Laser Ulas Biter, Gert-Jan van de Geijn, Christian Taube, Pieter S Hiemstra, Gert-Jan Braunstahl

Thorax Jul 2015, 70 (7) 659-667; DOI: 10.1136/thoraxjnl-2014-206712
Human tissue models for a human disease: what are the barriers?
Joanna Edwards, Maria Belvisi, Sven-Erik Dahlen, Stephen Holgate, Anthony Holmes

Thorax Jul 2015, 70 (7) 695-697; DOI: 10.1136/thoraxjnl-2014-206648

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