Table 1

Predefined criteria for case definition and diagnostic categories

CategoryLikely diagnosis of TBCriteria
1Culture-confirmed TBMicrobiological culture of MTB, and clinical and radiological findings suggestive of TB
2Highly probable TBClinical and radiological features highly suggestive of TB and unlikely to be caused by other diseases, a decision to treat made by a clinician, appropriate response to therapy and cytological evidence (presence of a granuloma) if available
3Clinically indeterminate diagnosisFinal diagnosis of TB neither highly probable nor reliably excluded
4Highly unlikely or TB excludedOther diagnosis made other than TB (eg, sarcoidosis, cancer or lymphoma)
  • MTB, Mycobacterium tuberculosis; TB, tuberculosis.