Comparison of chemicals detected in vaping products (unheated liquids) used in in vivo and in vitro exposure experiments
| Chemicals | CBD-Vape (CalmVape from The Kind Group) | Nic-Vape (Juul by Juul Labs) |
| CBD | 43.9 mg/mL | Not detected |
| Δ−9 Tetrahydrocannabinol | Not detected | Not detected |
| Nicotine | Not detected | 48.9 mg/mL |
| Solvent | MCT (medium chain triglycerides) – mixture of caprylic acid (C8), capric acid (C10), and lauric acid (C12) | Mixture of propylene glycol and vegetable glycerin |
| Flavourings and terpenes | Amylene hydrate (pungent); Benzyl alcohol (chemical, fruity cherry, almond, balsamic, bitter); Carvone (sweet, minty, spearmint, carvone, caraway); Linalol (citrus, orange, lemon, floral, waxy, aldehydic, woody); Caryophyllene (spicy, clove, woody, nut skin, powdery, peppery); Octanoic acid (rancid, soapy, cheesy, fatty, brandy); Decanoic acid, methyl ester (fatty, oily, fruity); Octanoic acid, methyl ester (green, fruity, waxy, citrus, aldehydic and fatty); Caryophyllene oxide (dry, woody, cedar, old wood, carrot, ambrette); Cherry propanol (fruity, cherry, sweet, hay-like with cereal and bread like nuances); Cis-carveol (caraway); Ethanone, 1-(4-methylphenyl)- (sweet, creamy, fruity, cherry and heliotropine-like) | Amylene hydrate (pungent); 2-Propanol, 1,1’-oxybis- (alcoholic); Benzaldehyde, 3,4-dimethoxy- (sweet, creamy, vanilla); Azolidine (fishy); Triethyl citrate (mild fruity wine); Butyrolactone (milky, creamy with fruity peach like afternotes) |
| Other additives | Not detected | Benzoic acid (combines with nicotine to create nicotine salt (nicotine benzoate)) |
CBD, cannabidiol; MCT, medium chain triglycerides.