Table 3

Results of secondary endpoints for the IG and CG

Baseline3 months6 months
IGCGP valueEffect size (95% CI)IGCGP valueEffect size (95% CI)IGCGP valueEffect size (95% CI)
CAT points16.53 (7.15)16.00 (7.12)0.7730.075
(−0.432 to 0.581)
15.53 (8.26)18.70 (6.71)0.109−0.421
(−0.931 to 0.093)
15.13 (8.58)19.72 (6.42)0.024−0.605
(−1.124 to to 0.080)
STST repetitions19.07 (5.77)16.87 (7.07)0.1960.341
(0.175 to 0.853)
22.87 (8.00)16.83 (7.64)0.0040.771
(0.243 to
1.293)
22.66 (7.23)19.45 (9.09)0.1430.390
(−0.131 to 0.908)
CRQ domains
Dyspnoea points4.54 (1.45)4.48 (1.19)0.8810.039
(−0.467 to 0.545)
4.51 (1.68)3.96 (1.40)0.1700.359
(−0.153 to 0.868)
4.54 (1.65)3.69 (1.31)0.0330.570
(0.047 to 1.089)
Fatigue points4.60 (1.22)4.68 (1.31)0.820−0.059
(−0.565 to 0.447)
4.31 (1.36)3.74 (1.13)0.0850.453
(−0.062 to 0.963)
4.50 (1.28)3.72 (1.36)0.0280.586
(0.062 to 1.105)
Emotional function points5.40 (1.07)5.14 (0.97)0.3250.256
(−0.253 to 0.763)
4.90 (1.31)4.41 (1.32)0.1610.367
(−0.145 to 0.875)
4.92 (1.27)4.54 (1.40)0.2830.282
(−0.232 to 0.794)
Mastery points5.27 (1.23)4.97 (1.27)0.3690.234
(−0.275 to 0.740)
5.18 (1.44)4.63 (1.64)0.1800.351
(−0.161 to 0.859)
5.08 (1.50)4.48 (1.51)0.1310.399
(−0.118 to 0.913)
Total CRQ points4.95 (1.07)4.82 (0.97)0.6180.129
(−0.378 to 0.636)
4.72 (1.31)4.19 (1.18)0.1020.429
(0.085 to 0.940)
4.76 (1.30)4.11 (1.26)0.0560.508
(−0.013 to 1.024)
Feeling thermometer degrees61.57 (19)61.57 (17)1.0000.000
(−0.506 to 0.506)
65.0 (20)63.50 (20)0.7720.075
(−0.431 to 0.581)
66.43 (18)58.93 (21)0.1470.383
(−0.134 to 0.896)
HADS-A points4.10 (3.33)4.10 (3.50)1.0000.000
(−0.506 to 0.506)
4.60 (3.74)6.10 (4.16)0.147−0.380
(−0.889 to 0.133]
4.43 (3.50)5.34 (4.19)0.368−0.236
(−0.748 to 0.277)
HADS-D points4.23 (2.90)4.23 (3.69)1.0000.000
(−0.506 to 0.506)
4.50 (2.74)6.03 (4.41)0.111−0.418
(−0.928 to 0.095)
4.20 (2.95)6.55 (5.08)0.033−0.569
(−1.087 to −0.046)
HADS total points8.33 (5.60)8.33 (6.47)1.0000.000
(−0.506 to
0.506)
8.33 (5.60)8.33 (6.47)1.0000.000
[−0.506 to 0.506)
8.33 (5.60)8.33 (6.47)1.0000.000
(−0.506 to 0.506)
Duration of sleep (hours)7.61 (1.36)7.73 (1.08)0.703−0.102 (0.621 to 0.418)7.32 (1.28)7.49 (1.89)0.704−0.105
(−0.644 to 0.434)
7.60 (1.31)7.13 (1.69)0.2940.311
(−0.269 to 0.888)
Sleep efficiency (%)91.71 (3.20)90.84 (3.33)0.3210.265 (−0.257 to 0.786)92.39 (2.37)90.97 (2.73)0.0480.555
(0.004 to 1.102)
91.95 (2.28)90.75 (2.93)0.1200.465
(−0.120 to 1.046)
  • Data are presented as mean and SD, and all p values were obtained from the t-tests.

  • CAT, COPD Assessment Test; CG, control group; CRQ, Chronic Respiratory Disease Questionnaire; HADS, Hospital Anxiety and Depression Scale; HADS-A, Hospital Anxiety and Depression Scale–Anxiety Subscale; HADS-D, Hospital Anxiety and Depression Scale–Depression Subscale; IG, intervention group; STST, Sit-to-Stand Test.