Table 1

Comparison of chemicals detected in vaping products (unheated liquids) used in in vivo and in vitro exposure experiments

ChemicalsCBD-Vape (CalmVape from The Kind Group)Nic-Vape (Juul by Juul Labs)
CBD43.9 mg/mLNot detected
Δ−9 TetrahydrocannabinolNot detectedNot detected
NicotineNot detected48.9 mg/mL
SolventMixture of propylene glycol and vegetable glycerinMCT (Medium Chain Triglycerides) – Mixture of caprylic acid (C8), capric acid (C10), and lauric acid (C12)
Flavourings and terpenesAmylene hydrate (pungent); Benzyl alcohol (chemical, fruity cherry, almond, balsamic, bitter); Carvone (sweet, minty, spearmint, carvone, caraway); Linalol (citrus, orange, lemon, floral, waxy, aldehydic, woody); Caryophyllene (spicy, clove, woody, nut skin, powdery, peppery); Octanoic acid (rancid, soapy, cheesy, fatty, brandy); Decanoic acid, methyl ester (fatty, oily, fruity); Octanoic acid, methyl ester (green, fruity, waxy, citrus, aldehydic and fatty); Caryophyllene oxide (dry, woody, cedar, old wood, carrot, ambrette); Cherry propanol (fruity, cherry, sweet, hay-like with cereal and bread like nuances); Cis-carveol (caraway); Ethanone, 1-(4-methylphenyl)- (sweet, creamy, fruity, cherry and heliotropine-like)Amylene hydrate (pungent); 2-Propanol, 1,1’-oxybis- (alcoholic); Benzaldehyde, 3,4-dimethoxy- (sweet, creamy, vanilla); Azolidine (fishy); Triethyl citrate (mild fruity wine); Butyrolactone (milky, creamy with fruity peach like afternotes)
Other additivesNot detectedBenzoic acid (combines with nicotine to create nicotine salt (nicotine benzoate))
  • CBD, cannabidiol; MCT, medium chain triglycerides.