Tuberculosis studies meeting inclusion criteria using passive case finding including clinically diagnosed tuberculosis cases
| Study title | Study type | Country | Age (median, IQR) | Male (%) | Setting | Presumptive TB (included/ eligible) | Diagnosed with tuberculosis | Not tuberculosis | |||||
| Laboratory (bacteriological) | Clinical | Total (%) | HIV | Total (%) | HIV | ||||||||
| Boehme et al (2011)19 | Feasibility, diagnostic accuracy and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study | Cross-sectional Study | South Africa | 36, 29–46 | 51 | Health centre | 1968/1968 | 473 | 824 | 1297 (66) | NR | 671 (34) | NR |
| Uganda | 32 26–38 | 54 | General hospital | 307/307 | 146 | 17 | 163 (53) | NR | 144 (47) | NR | |||
| Bruchfeld et al (2002)20 | Evaluation of outpatients with suspected pulmonary tuberculosis in a high HIV prevalence setting in Ethiopia: Clinical, Diagnostic and epidemiological characteristics | Cross-sectional study | Ethiopia | 33† | 56.3† | General hospital | 493/509 | 168 | 113 | 281 (57) | 148/281 | 212 (43) | 73 /212 |
| Jayasooriya et al (2019)6 | The burden of non-TB lung disease presenting to TB clinics in the Gambia: Preliminary data in the Xpert MTB/rif era | Cross-sectional Study | The Gambia | 40†
28–47 | 50† | Research clinic | 233/239 | 114 | 17 | 131 (56) | 17/131 | 102 (44) | 12 /102 |
| Munyati et al (2005)21 | Chronic cough in primary healthcare attendees, Hasrare, Zimbabwe: diagnosis and impact of HIV infection | Cross-sectional Study | Zimbabwe | 33 | 48 | Health centre | 544/550 | 184 | 50 | 234 (43) | 207/234 | 310 (57) | 247 /310 |
| Nliwasa et al (2016)22 | The Sensitivity and Specificity of Loop-Mediated Isothermal Amplification (LAMP) Assay for Tuberculosis Diagnosis in Adults with Chronic Cough in Malawi | Cross-sectional Study | Malawi | 32 25–41 | 48 | Health centre | 233/273 | 53 | 3 | 56 (24) | 24/56 | 177 (76) | 97 /177 |
| Reither et al (2010)23 | Evaluation of diagnos TB AG, a flow-through immunoassay for rapid detection of pulmonary tuberculosis | Cross-sectional Study | Tanzania | 36 | 47.4 | Research clinic | 171/202 | 45 | 33 | 78 (46) | 51/78 | 93 (54) | 50 /93 |
| Theron et al (2011)17 | Evaluation of the Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in a high prevalence setting | Cross-sectional Study | South Africa | 36 18–83* | 68 | Health centre | 480/496 | 141 | 182 | 323 (67) | 46/323 | 157 (33) | 84 /157 |
*(Range).
†Not TB patients.
NR, not recorded; TB, tuberculosis.