Usual care (n=1155) | FF/VI (n=1081) | |
Change from baseline in ACT total score | ||
Week 12 | ||
n | 1104 | 1021 |
LS mean change (SE) | 1.89 (0.115) | 3.40 (0.120) |
Difference* (95% CI) | 1.51 (1.19 to 1.83), p<0.001 | |
Week 24 | ||
n | 1063 | 988 |
LS mean change (SE) | 1.75 (0.125) | 3.24 (0.130) |
Difference* (95% CI) | 1.49 (1.14 to 1.84), p<0.001 | |
Week 40 | ||
n | 1048 | 957 |
LS mean change (SE) | 1.67 (0.127) | 3.13 (0.134) |
Difference* (95% CI) | 1.45 (1.10 to 1.81), p<0.001 | |
Week 52 | ||
n | 1046 | 962 |
LS mean change (SE) | 1.60 (0.124) | 3.05 (0.130) |
Difference* (95% CI) | 1.45 (1.10 to 1.80), p<0.001 | |
Number of salbutamol inhalers prescribed during the study | ||
n (patients) | 1154 | 1076 |
LS mean (SE) | 8.0 (0.14) | 7.2 (0.14) |
Difference* (95% CI) | −0.8 (−1.2 to −0.5), p<0.001 |
*FF/VI vs usual care.
ACT, Asthma Control Test; FF/VI, fluticasone furoate/vilanterol; LS, least squares.