Outcomes of the probabilistic analysis over 20 years for 100 patients with COPD
No azithromycin (95% CI) | Azithromycin (95% CI) | Difference (95% CI) | |
Total exacerbations (n) | 2047 (1635 to 2567) | 1931 (1545 to 2435) | −116 (−176 to −63) |
Severe or very severe exacerbations (n) | 280 (200 to 397) | 265 (190 to 375) | −15 (−25 to −8) |
Cumulative incidence of hearing loss (n) | 24 (13 to 34) | 28 (15 to 40) | 4 (1 to 7) |
Average episodes of GI symptoms (n) | 19 (17 to 21) | 23 (15 to 33) | 4 (−3 to 13) |
Mortality due to exacerbation (n) | 40 (28 to 54) | 38 (26 to 52) | −2 (−3 to −1) |
Other mortality (Including CV death) (n) | 34 (28 to 39) | 35 (29 to 40) | 1 (0 to 2) |
Life years | 1170 (1011 to 1303) | 1204 (1053 to 1328) | 34 (18 to 51) |
Total QALYs | 555.5 (482.7 to 624.4) | 573.5 (504.7 to 637.8) | 17.9 (6.2 to 30.0) |
Results are reported for 100 patients.
GI, gastrointestinal; QALY, quality-adjusted life year.