Table 2

Outcomes of the probabilistic analysis over 20 years for 100 patients with COPD

No azithromycin (95% CI)Azithromycin (95% CI)Difference (95% CI)
Total exacerbations (n)2047 (1635 to 2567)1931 (1545 to 2435)−116 (−176 to −63)
Severe or very severe exacerbations (n)280 (200 to 397)265 (190 to 375)−15 (−25 to −8)
Cumulative incidence of hearing loss (n)24 (13 to 34)28 (15 to 40)4 (1 to 7)
Average episodes of GI symptoms (n)19 (17 to 21)23 (15 to 33)4 (−3 to 13)
Mortality due to exacerbation (n)40 (28 to 54)38 (26 to 52)−2 (−3 to −1)
Other mortality (Including CV death) (n)34 (28 to 39)35 (29 to 40)1 (0 to 2)
Life years1170 (1011 to 1303)1204 (1053 to 1328)34 (18 to 51)
Total QALYs555.5 (482.7 to 624.4)573.5 (504.7 to 637.8)17.9 (6.2 to 30.0)
  • Results are reported for 100 patients.

  • GI, gastrointestinal; QALY, quality-adjusted life year.