Clinical and respiratory parameters, stratified by prior tuberculosis status
| Post-tuberculosis cases | Comparison group | P value | |
| Self-reported clinical and respiratory symptoms* | n=68 | n=91 | |
| Cough, n (%) | 21 (30.9) | 20 (22.0) | 0.176† |
| Sputum, n (%) | 8 (11.8) | 7 (7.7) | 0.397† |
| Wheeze, n (%) | 6 (8.8) | 9 (9.9) | 0.819† |
| Easy fatigability, n (%) | 15 (22.1) | 10 (11.0) | 0.095† |
| Chest pain, n (%) | 17 (25.0) | 15 (16.5) | 0.105† |
| Failure to gain weight, n (%) | 19 (27.9) | 13 (14.3) | 0.026† |
| Any respiratory symptom, n (%) | 35 (51.5) | 34 (37.4) | 0.068† |
| Child self-report quality of life | n=63 | n=89 | |
| Physical health, median % (IQR) | 68.8 (56.3–93.8) | 81.3 (62.5–100) | 0.016‡ |
| Emotional functioning, median % (IQR) | 80.0 (60.0–90.0) | 80.0 (60.0–80.0) | 0.538‡ |
| Social functioning, median % (IQR) | 90.0 (80.0–100) | 90.0 (80.0–100) | 0.333‡ |
| School functioning, median % (IQR) | 70.0 (60.0–90.0) | 80.0 (60.0–90.0) | 0.221‡ |
| Psychosocial health, median % (IQR) | 80.0 (70.0–86.7) | 80.0 (70.0–90.0) | 0.676‡ |
| Total score, median % (IQR) | 73.9 (65.2–89.1) | 78.3 (67.4–89.1) | 0.215‡ |
| Parent-report quality of life | n=63 | n=82 | |
| Physical health, median % (IQR) | 87.5 (68.8–93.8) | 100 (87.5–100) | <0.001‡ |
| Emotional functioning, median % (IQR) | 80.0 (70.0–100) | 90.0 (80.0–100) | 0.001‡ |
| Social functioning, median % (IQR) | 100 (90.0–100) | 100 (100–100) | 0.019‡ |
| School functioning, median % (IQR) | 80.0 (60.0–100) | 80.0 (60.0–100) | 0.347‡ |
| Psychosocial health, median % (IQR) | 73.3 (80.0–93.3) | 90.0 (80.0–96.7) | 0.004‡ |
| Total score, median % (IQR) | 82.6 (71.7–93.5) | 91.3 (82.6–97.8) | <0.001‡ |
| Spirometry | n=52 | n=86 | |
| FEV1 z-score, mean (SD) | −1.52 (−0.99) | −0.83 (−0.84) | <0.001‡ |
| FVC z-score, mean (SD) | −1.32 (1.02) | −0.87 (0.89) | 0.014‡ |
| FEV1/FVC ratio z-score, mean (SD) | −0.54 (0.91) | −0.03 (0.81) | 0.001‡ |
| Abnormal spirometry, n (%) | 20 (38.5) | 15 (17.4) | 0.009† |
| Pattern of spirometry | |||
| Normal, n (%) | 32 (61.5) | 71 (82.6) | 0.029§ |
| Obstructive, n (%) | 1 (1.9) | 2 (2.3) | |
| Restrictive, n (%) | 19 (36.4) | 13 (15.1) |
*Question read as follows: ‘Have you had any of the following occurring often or repeatedly in the last 6 months?’.
†P values obtained from fitting a univariable mixed effect logistic regression where prior TB status is the independent variable.
‡P value based on the non-parametric Somers’ D measure, accounting for clustering.
§P values obtained from fitting a univariable mixed effect logistic regression where prior TB status is the dependent variable.
FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; TB, tuberculosis.