Clinical and laboratory characteristics of the patients with ARDS
| Characteristic | ARDS |
| Total no. | 50 |
| Sex (no. male/no. female) | 39/11 |
| Age (years), median (IQR) | 69.5 (52.8–77.0) |
| Clinical variables | |
| Cause of disease, n (%) | |
| Bacterial pneumonia | 31/50 (62) |
| Viral pneumonia | 3/50 (6) |
| Non-pulmonary sepsis | 6/50 (24) |
| Aspiration | 7/50 (14) |
| Others* | 3/50 (6) |
| Disease severity, n (%) | |
| Mild | 2/50 (4) |
| Moderate | 31/50 (62) |
| Severe | 17/50 (34) |
| Mortality, n (%) | 25/50 (50) |
| Mild | 0/2 (0) |
| Moderate | 12/31 (38.7) |
| Severe | 13/17 (76.5) |
| PEEP (cmH2O), median (IQR) | 12.0 (10.0–13.0) |
| Plateau pressure (cmH2O), median (IQR) | 28.0 (24.5–31.5) |
| ECMO (%) | 9/50 (18) |
| Laboratory variables, median (IQR) | |
| Leucocyte count (cells/μL) | 12 300 (7900–15 225) |
| Lymphocyte count (cells/μL) | 620 (402.5–1073) |
| Monocyte count (cells/μL) | 485 (205.0–927.5) |
| Neutrophil count (cells/μL) | 10 110 (6163–13 813) |
| Haemoglobin level (g/dL) | 9.8 (8.7–11.0) |
| Platelet count (×103 cells/µL) | 173.0 (86.8–242.3) |
| PaCO2 (mm Hg) | 42.0 (36.0–48.0) |
| PaO2 (mm Hg) | 77.5 (65.6–86.7) |
| FiO2 (mm Hg) | 0.6 (0.55–0.80) |
| PaO2/FiO2 ratio | 119.0 (83.8–141.0) |
| Total protein level (g/dL) | 5.5 (4.8–6.1) |
| Albumin (g/dL) | 2.6 (2.3–2.9) |
| AST (U/L) | 42.0 (22.0–78.0) |
| ALT (U/L) | 23.0 (13.5–60.5) |
| BUN (mg/dL) | 29.8 (20.9–50.4) |
| Creatinine (mg/dL) | 1.0 (0.7–1.69) |
| CRP level (mg/dL) | 17.2 (9.1–27.2) |
*included trauma, pancreatitis, and hepatitis.
ALT, alanine transaminase; ARDS, acute respiratory distress syndrome; AST, aspartate transaminase; BUN, blood urea nitrogen; CRP, C reactive protein; ECMO, extracorporeal membrane oxygenation; FiO2, fraction of inspired oxygen; PaCO2, partial pressure of arterial carbon dioxide; PaO2, partial pressure of arterial oxygen; PaO2/FiO2, ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen; PEEP, positive end expiratory pressure.