Regression coefficients for log-transformed absolute MAIT cell numbers with respect to clinical and laboratory findings in patients with ARDS
Variables | β | 95% CI | P value | |
Lower | Upper | |||
Sex (male) | −0.579 | −1.254 | 0.095 | 0.091 |
Age (years) | −0.007 | −0.022 | 0.009 | 0.393 |
Disease severity | −0.746 | −1.235 | −0.257 | 0.004 |
Mortality | −0.622 | −1.169 | −0.075 | 0.027 |
PEEP (cmH2O) | −0.022 | −0.132 | 0.087 | 0.680 |
Plateau pressure (cmH2O) | 0.026 | −0.066 | 0.119 | 0.557 |
ECMO | 0.178 | −0.580 | 0.936 | 0.638 |
Leucocyte count (cells/μL) | 0.0001 | 0.0001 | 0.001 | 0.076 |
Lymphocyte count (cells/μL) | 0.0001 | 0.0001 | 0.001 | 0.012 |
Monocyte count (cells/μL) | 0.0001 | 0.0001 | 0.001 | 0.440 |
Neutrophil count (cells/μL) | 0.0001 | 0.0001 | 0.0001 | 0.146 |
Haemoglobin (g/dL) | 0.114 | −0.073 | 0.302 | 0.227 |
Platelet count (103 cells/µL) | 0.001 | −0.002 | 0.003 | 0.629 |
PaCO2 (mm Hg) | 0.009 | −0.016 | 0.034 | 0.485 |
PaO2 (mm Hg) | 0.004 | −0.007 | 0.015 | 0.503 |
FiO2 (mm Hg) | −1.827 | −3.284 | −0.370 | 0.015 |
PaO2/FiO2 ratio | 0.010 | 0.003 | 0.016 | 0.004 |
Total protein (g/dL) | −0.237 | −0.550 | 0.075 | 0.133 |
Albumin (g/dL) | 0.526 | −0.164 | 1.216 | 0.132 |
AST (U/L) | 0.0001 | −0.001 | 0.0001 | 0.647 |
ALT (U/L) | 0.0001 | −0.002 | 0.002 | 0.806 |
BUN (mg/dL) | −0.001 | −0.016 | 0.015 | 0.948 |
Creatinine (mg/dL) | 0.063 | −0.168 | 0.293 | 0.588 |
CRP (mg/dL) | −0.002 | −0.031 | 0.027 | 0.885 |
ALT, alanine transaminase; ARDS, Acute respiratory distress syndrome; AST, aspartate transaminase; BUN, blood urea nitrogen; CRP, C reactive protein; ECMO, extracorporeal membrane oxygenation; FiO2, fraction of inspired oxygen; MAIT, mucosal-associated invariant T; PaCO2, partial pressure of arterial carbon dioxide; PaO2, partial pressure of arterial oxygen; PaO2/FiO2, ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen; PEEP, positive end expiratory pressure; β, regression coefficient.