IgG tests and SGRQ comparisons for all patients assessed at baseline and at end of TB therapy, using the CPA categorisation at the second time point
| Variables | Early TB therapy (n=128) | End of therapy (n=128) | P value | CPA (n=10) | non-CPA (n=118) | P value |
| Serology tests | ||||||
| Aspergillus-specific IgG (mg/L) | 9.2 (6.5–12.7) | 9.7 (6.9–14.2) | 0.078 | 24.2 (13.8–76.1) | 9 (6.6–13.1) | <0.001 |
| SGRQ scores | ||||||
| Symptoms | 37.2 (18.4–56.7) | 3 (0–22.5) | <0.001 | 23.3 (9.6–37.3) | 3 (0–21.1) | 0.002 |
| Impact | 39 (21.5–51.9) | 4 (0–13.6) | <0.001 | 9.2 (5–37.7) | 3.7 (0–13.1) | 0.007 |
| Activity | 21.9 (0–59.4) | 0 (0–8.4) | <0.001 | 23.6 (0–53.9) | 0 (0–0) | 0.002 |
| Total | 35.9 (16.3–51.4) | 4.8 (4–12.8) | <0.001 | 17.4 (8–36.8) | 3.4 (0–12.2) | 0.003 |
Data are given as median (IQR).
Bold values indicate statistical significance.
CPA, chronic pulmonary aspergillosis; SGRQ, St Georges Respiratory Questionnaire.