The demographic data for the human subjects evaluated for lung FLCN protein
| Variables | Control (n=5) | COPD (n=6) |
| Age | 62.0±8.9 | 58.7±3.4 |
| Sex | 3M/2F | 3M/3F |
| Smoking (pack years) | 37±9 | 55±33 |
| FEV1/FVC | N/A | 0.33±0.10 |
| Per cent FEV1 | N/A | 19.3±4.3 |
| Per cent DLCO | N/A | 29.0±5.6 |
The diagnosis and stage of COPD are determined by spirometric data. All COPD subjects belong to the very severe stage. Control represents smokers without known lung diseases. Data are expressed as mean±SD Their age and smoking history are not statistically different.
COPD, chronic obstructive pulmonary disease ; DLCO, the diffusing capacity of the lungs for carbon monoxide; FEV1, forced expiratory volume in 1s; FLCN, folliculin; FVC, forced vital capacity; N/A, not available.