Table 2

Tuberculosis (TB) studies meeting inclusion criteria using passive case finding not including clinically diagnosed TB cases

Study titleStudy typeCountryAge
(median, IQR)		Male (%)SettingPresumptive TB (included/ eligible)Diagnosed with TBNot TB
Laboratory
(bacteriological)		ClinicalTotal
(%)		HIVTotal
(%)		HIV
Cuevas et al (2011)24A multicountry non-inferiority cluster randomised trials of frontloaded smear microscopy for the diagnosis of pulmonary tuberculosisCluster randomised trialEthiopia33.7*
(±14.1)		52.8Health centre1770/19095860586
(33)		0/5861184
(67)		NR
Nigeria34.4*
(±10.7)		51.9Health centre1196/12382330233
(19)		0/233963
(81)		NR
Dorman et al (2018)25Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy studyCross-sectional studySouth Africa (Cape Town)41,
34–49		41District hospital152/15227NR27
(18)		NR125
(82)		NR
South Africa (Johannesburg)34,
30–43		63District hospital234/23474NR74
(32)		NR160
(68)		NR
Kenya33,
26–44		51District hospital135/13528NR28
(21)		NR107
(79)		NR
Uganda30,
26–39		64District hospital181/18167NR67
(37)		NR114
(63)		NR
Hanrahan et al (2014)26Xpert MTB/RIF as a measure of sputum bacillary burden. Variation by HIV status and immunosuppressionCross-sectional studySouth Africa37,
29–46		38Health centre2091/24064060406
(19)		NR1685
(81)		NR
Lawson et al (2008)27Clinical presentation of adults with pulmonary tuberculosis with and without HIV infection in NigeriaCross-sectional studyNigeria33*
(±10)		61District hospital1186/13217310731
(62)		329†
/625		455
(38)		217†
/377
Ling et al (2011)18Are interferon-gamma release assays useful for diagnosing active tuberculosis in a high-burden setting?Cross-sectional studySouth Africa40*
(±12)		66Health centre395/5001380138
(35)		43
/138		257
(65)		65
/257

  • *Age, mean (±SD).

  • †Not all tested, denominator.

  • NR, not recorded.