Baseline demographics of the study population
| Parameters | Patients with bronchiectasis N=34 | Healthy volunteers N=6 | ||
| Mild n=10 | Moderate n=15 | Severe n=9 | ||
| Age (years) | 55 (4.1) | 65 (2.2) | 64 (2.2) | 52 (6.8) |
| Biological sex (% female) | 40 | 60 | 22 | 80 |
| Aetiology | ||||
| Idiopathic | 10 (100%) | 12 (80%) | 6 (67%) | |
| Postinfective | 3 (20%) | 3 (33%) | ||
| Total WCC (×109/L) | 6 (0.5) | 6.3 (0.4) | 9.3 (1.1) | 5.9 (0.5) |
| Neutrophils | 3.3 (0.3) | 4.1 (0.3) | 6.6 (1.1) | 3.5 (0.3) |
| Eosinophils | 0.2 (0.04) | 0.3 (0.07) | 0.2 (0.06) | 0.2 (0.06) |
| Monocytes | 0.5 (0.03) | 0.6 (0.05) | 0.7 (1) | 0.5 (0.05) |
| ESR (mm/hour) | 6.7 (1.8) | 13.2 (2.9) | 19.6 (6.8) | 4.8 (1) |
| CRP (mg/L) | 2.8 (0.5) | 4 (1) | 16 (7.4) | 3.2 (1.1) |
| FEV1 % predicted (L) | 95 (5.5) | 82 (4) | 55 (6.5) | – |
| FVC % predicted (L) | 111 (6) | 97 (4) | 84 (6) | – |
| TLCO % predicted (SI) | 94% (4.9) | 82% (4.2.) | 74% (7.8) | – |
| KCO % predicted (SI) | 106% (4.5) | 97% (3.7) | 100% (7.2) | – |
| Chronic colonisation | 5 (50%) | 12 (86%) | 8 (89%) | – |
| Exacerbations in the last year | 0.4 (0.3) | 2.4 (0.5) | 4.2 (0.9) | – |
| Hospital admissions in the last year | 0 | 0.05 (0.05) | 0.7 (0.2) | – |
Data presented as mean (±SE of mean).
CRP, C reactive protein; ESR, erythrocyte sedimentation rate; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; KCO, transfer coefficient corrected for alveolar volume; TLCO, transfer factor for the lung for carbon monoxide; WCC, white cell count.