Spearman correlation coefficients of radiographic and dyspnoea scores with pulmonary function, 6-minute walk distance, frailty and symptoms
DLCO (% predicted) | FVC (% predicted) | 6MWD (m) | |||||||
CT pattern | R 2 | r | P value | R 2 | r | P value | R 2 | r | P value |
Ground glass opacities | 0.12 | −0.34 | 0.003* | 0.06 | −0.25 | 0.03* | 0 | −0.02 | 0.92 |
Reticulations | 0.41 | −0.64 | <0.001* | 0.04 | −0.21 | 0.07 | 0 | −0.02 | 0.8 |
Traction bronchiectasis | 0.24 | −0.49 | <0.001* | 0.05 | −0.23 | 0.04* | 0 | −0.05 | 0.69 |
Frailty phenotype score | Cough scale | UCSD SOBQ | |||||||
CT pattern | R 2 | r | P value | R 2 | r | P value | R 2 | r | P value |
Ground glass opacities | 0.21 | 0.46 | <0.001* | 0 | 0.07 | 0.56 | 0.02 | 0.14 | 0.23 |
Reticulations | 0.05 | 0.23 | 0.04* | 0.07 | 0.26 | 0.02* | 0 | 0.05 | 0.66 |
Traction bronchiectasis | 0.03 | 0.16 | 0.17 | 0.06 | 0.25 | 0.03* | 0 | 0.07 | 0.57 |
DLCO (% predicted) | FVC (% predicted) | 6MWD (m) | |||||||
R 2 | r | P value | R 2 | r | P value | R 2 | r | P value | |
UCSD SOBQ | 0.02 | −0.14 | 0.24 | 0.06 | −0.25 | 0.04* | 0.06 | −0.25 | 0.03* |
Frailty phenotype score | Grip strength (kg) | Gait speed (m/s) | |||||||
R2 | r | P value | R2 | r | P value | R2 | r | P value | |
UCSD SOBQ | 0.22 | 0.47 | <0.001* | 0.14 | −0.37 | 0.001* | 0.05 | −0.21 | 0.06 |
*Significant after controlling for false discovery using the Benjamini-Hochberg method at a false discovery rate of 0.10.
DLCO, diffusion capacity for carbon monoxide; 6MWD, 6-minute walk distance; UCSD SOBQ, University of California San Diego Shortness of Breath Questionnaire.