Table 1

Spearman correlation coefficients of radiographic and dyspnoea scores with pulmonary function, 6-minute walk distance, frailty and symptoms

DLCO (% predicted)FVC (% predicted)6MWD (m)
CT pattern R 2 r P value R 2 r P value R 2 r P value
Ground glass opacities0.12−0.34 0.003* 0.06−0.25 0.03* 0−0.020.92
Reticulations0.41−0.64 <0.001* 0.04−0.210.070−0.020.8
Traction bronchiectasis0.24−0.49 <0.001* 0.05−0.23 0.04* 0−0.050.69
Frailty phenotype score Cough scale UCSD SOBQ
CT pattern R 2 r P value R 2 r P value R 2 r P value
Ground glass opacities0.210.46 <0.001* 00.070.560.020.140.23
Reticulations0.050.23 0.04* 0.070.26 0.02* 00.050.66
Traction bronchiectasis0.030.160.170.060.25 0.03* 00.070.57
DLCO (% predicted) FVC (% predicted) 6MWD (m)
R 2 r P value R 2 r P value R 2 r P value
UCSD SOBQ0.02−0.140.240.06−0.25 0.04* 0.06−0.25 0.03*
Frailty phenotype score Grip strength (kg) Gait speed (m/s)
R2 r P value R2 r P value R2 r P value
UCSD SOBQ0.220.47 <0.001* 0.14−0.37 0.001* 0.05−0.210.06
  • *Significant after controlling for false discovery using the Benjamini-Hochberg method at a false discovery rate of 0.10.

  • DLCO, diffusion capacity for carbon monoxide; 6MWD, 6-minute walk distance; UCSD SOBQ, University of California San Diego Shortness of Breath Questionnaire.