Table 2

Effect of randomisation to cow’s milk free diet on wheeze, atopy and asthma

Outcome and age (years)Intervention groupControl groupCrude OR (95% CI); p value*Adjusted OR (95% CI); p value
Wheeze age 180/227 (35.2%)78/234 (33.3%)1.09 (0.74 to 1.6); 0.671.04 (0.69 to 1.57); 0.85
Atopy age 146/232 (19.8%)39/237 (16.5%)1.26 (0.78 to 2.01); 0.341.29 (0.78 to 2.12); 0.30
Wheeze age 758/215 (27.0%)70/231 (30.3%)0.85 (0.56 to 1.28); 0.440.89 (0.58 to 1.36); 0.59
Atopy age 758/208 (27.9%)51/222 (23.0%)1.30 (0.84 to 2.00); 0.241.39 (0.89 to 2.18); 0.15
Asthma age 734/215 (15.8%)40/231 (17.3%)0.90 (0.54 to 1.48); 0.670.98 (0.54 to 1.50); 0.68
Wheeze age 1561/180 (33.9%)54/176 (30.7%)1.16 (0.74 to 1.81); 0.521.10 (0.70 to 1.74); 0.67
Asthma age 1542/180 (23.3%)34/176 (19.3%)1.27 (0.76 to 2.11); 0.361.18 (0.70 to 1.99); 0.54
Wheeze age 2354/146 (37.0%)44/153 (28.8%)1.45 (0.90 to 2.36); 0.1301.43 (0.87 to 2.37); 0.16
Atopy age 2341/58 (70.7%)29/61 (47.5%)2.66 (1.25 to 5.67); 0.012.97 (1.30 to 6.80); 0.01
Asthma age 2334/146 (22.8%)19/153 (12.6%)2.14 (1.16 to 3.96); 0.012.07 (1.09 to 3.91); 0.03
  • *Adjusted for social class at age 1, parental allergy, gender and breast feeding.