Baseline characteristics of the subjects and indexes calculated using rectal organoid morphology analysis (ROMA)
| CF | Non-CF | p value | |
| n | 167 | 22* | |
| IR | 1.11 (0.93–1.34) | 0.76 (0.61–0.88) | <0.001 |
| CI | 0.59 (0.49–0.70) | 0.79 (0.73–0.84) | <0.001 |
| Age (years) | 18 (0–60) | 44 (0–77) | <0.001 |
| Gender | 85 male (51%) | 11 male (50%) | >0.999 |
| 82 female (49%) | 11 female (50%) | ||
| SCC (mmol/L) (n=164) | 97.61 (36–160) | ||
| SCC low (<87 mmol/L) or high (≥87 mmol/L) | 41 low (25%) | ||
| 123 high (75%) | |||
| Pancreatic status (n=165) | 28 PS (17%) | ||
| 137 PI (83%) |
n or mean and range.
*7 carriers, 3 non-carriers, 2 autosomal dominant polycystic kidney disease, 6 ulcerative colitis, 1 polyp screening, 3 healthy controls included in a study about inflammatory bowel disease.
CF, cystic fibrosis; IR, intensity ratio; CI, circularity index; SCC, sweat chloride concentration; PI, pancreatic insufficient; PS, pancreatic sufficient