Absent | Present | T-test | |||||||
N | M | SD | Range | N | M | SD | Range | P value | |
Age (y) | 492 | 57.4 | 4.5 | 50–65 | 41 | 57.5 | 4.7 | 50–65 | NS |
Weight (kg) | 492 | 80 | 16 | 43–139 | 41 | 89 | 13 | 54–106 | NS |
Height (cm) | 492 | 171 | 9 | 146–199 | 41 | 177 | 9 | 151–197 | <0.0001 |
BMI (kg/m2) | 492 | 27 | 5 | 17–45 | 41 | 25 | 4 | 18–34 | 0.01 |
TLC (CTV) (L) | 492 | 5.2 | 1.2 | 2.3–10.1 | 41 | 7.1 | 9.4 | 5.5–9.2 | <0.0001 |
VC (L) | 492 | 3.9 | 0.9 | 1.9–7.3 | 40 | 4.8 | 0.9 | 2.5–6.4 | <0.0001 |
VC (% pred) | 491 | 110 | 15 | 60–154 | 40 | 112 | 13.2 | 78–139 | NS |
FEV1 (L) | 491 | 3.1 | 0.72 | 0.27–5.35 | 40 | 3.45 | 0.95 | 0.99–5.08 | 0.03 |
FEV1 (% pred) | 491 | 106 | 15 | 46–152 | 40 | 103 | 22 | 30–139 | NS |
DL,CO (mmol min-1 kPa-1) | 463 | 8.07 | 1.67 | 2.2–14.3 | 38 | 8.49 | 1.93 | 2.6–11.3 | NS |
DL,CO (% pred) | 460 | 91 | 13 | 42–170 | 38 | 89 | 17 | 29–117 | NS |
RV −950 (%) | 492 | 1.4 | 1.2 | 0–5 | 41 | 7.4 | 5.2 | 5–23 | |
Pack-years | 453 | 10.5 | 14.2 | 0–86 | 38 | 10.1 | 14.8 | 0–54 | NS |
rAiDA (µm) | 492 | 291 | 36 | 214–516 | 41 | 316 | 41 | 239–412 | <0.0001 |
AiDA, Airspace dimension assessment with nanoparticles; BMI, body mass index; TLC (CTV), total lung capacity measured by volumetric CT; DLCO, diffusing capacity for carbon monoxide; FEV1, forced expiratory flow in one second;NS, not significant; rAiDA, distal airspace radius measured with the AiDA method; RV-950, the relative volume of voxels in lung parenchyma with a Hounsfield Unit value less than -950; TLC, total lung capacity; VC, vital capacity.