Table 1

Demographic and clinical characteristics of the observational study cohort from UK Biobank

ParameterOverall study populationStudy participants with confirmed SARS-CoV-2 infectionStudy participants with recorded COVID-19-related hospitalisationStudy participants with COVID-19-related death
Number421 4691649968444
Age group (at study start) (years)
 40–491213 (0.29)<1000 (0)
 50–5997 372 (23.10)492 (29.84)141 (14.57)19 (4.28)
 60–69140 664 (33.37)400 (24.26)236 (24.38)71 (15.99)
 70–79174 520 (41.41)696 (42.21)549 (56.71)317 (71.40)
 80+7700 (1.83)59 (2.52)42 (4.34)37 (8.33)
Sex
 Female232 366 (55.13)787 (47.73)373 (38.53)164 (36.94)
 Male189 103 (44.87)862 (52.27)595 (61.47)280 (63.06)
Townsend quintile
 1 (most affluent)193 357 (45.88)563 (34.16)315 (32.54)147 (33.18)
 293 928 (22.29)362 (21.97)199 (20.56)84 (18.96)
 361 227 (14.53)273 (16.57)152 (15.70)74 (16.70)
 450 180 (11.91)277 (16.81)174 (17.98)87 (19.64)
 5 (most deprived)22 280 (5.29)173 (10.50)128 (13.22)51 (11.51)
 Not recorded497 (0.12)<1000
Body mass index
 Underweight1942 (0.46)<10<10<10
 Healthy134 323 (31.87)375 (22.74)168 (17.36)82 (18.47)
 Overweight177 246 (42.05)682 (41.36)394 (40.70)179 (40.32)
 Obese72 340 (17.16)338 (20.50)229 (23.66)99 (22.30)
 Severely obese27 957 (6.63)198 (12.01)142 (20.34)61 (13.73)
 Not recorded7661 (1.82)50 (3.03)32 (3.31)20 (4.50)
Ethnic group
 White394 113 (93.51)1429 (97.28)836 (86.27)401 (90.32)
 Mixed race2630 (0.62)13 (0.79)<10<10
 Asian/Asian British7453 (1.77)60 (3.64)32 (3.30)<10
 Chinese1421 (0.34)<10<10<10
 Other Asian1681 (0.40)13 (0.79)<10<10
 Black/Black British7615 (1.81)84 (5.09)60 (6.20)23 (5.18)
 Other4162 (0.99)31 (1.88)17 (1.76)<10
 Not recorded2394 (0.57)12 (0.73)<10<10
Last recorded smoking status
 Never-smoker248 952 (59.07)849 (51.49)440 (45.45)159 (35.81)
 Former smoker155 594 (36.91)717 (43.48)457 (47.21)223 (50.22)
 Light smoker (1–9/day)3947 (0.94)18 (1.09)12 (1.24)<10
 Moderate smoker (10–19/day)5799 (1.38)26 (1.58)25 (2.58)20 (4.50)
 Heavy smoker (20+/day)3965 (0.94)13 (0.79)14 (1.45)16 (3.60)
 Not recorded3212 (0.76)26 (1.58)200
Comorbidities not related to smoking
 Bronchiectasis545 (0.13)<10<10<10
 Chronic liver disease1204 (0.29)15 (0.91)13 (1.34)<10
 Cystic fibrosis<10<10<10<10
 Diabetes mellitus21 835 (5.18)177 (10.73)124 (12.81)71 (15.99)
 Interstitial lung disease284 (0.07)<10<10<10
Smoking-related comorbidities
 Asthma2382 (0.57)18 (1.09)11 (1.14)<10
 Atrial fibrillation8125 (1.93)62 (3.76)42 (4.34)30 (6.75)
 COPD3373 (0.80)29 (1.76)29 (3.00)19 (4.28)
 Chronic kidney disease704 (0.17)16 (0.97)<10<10
 Congestive cardiac failure1329 (0.32)26 (1.58)24 (2.48)15 (3.38)
 Hypertension1196 (0.28)11 (0.68)<10<10
 Ischaemic heart disease24 848 (5.90)175 (10.61)137 (14.15)77 (17.34)
 Lung cancer696 (0.17)10 (0.61)<10<10
  • Figures in parentheses correspond to the column percentage.