Prevalence of peripheral eosinophilia among subjects with COPD without asthma history and COPD with asthma history, stratified by gender, race, age groups, smoking status and exhaled FeNO levels
| Demographic variable | COPD without asthma history (N=2 655 739) | COPD with asthma history (N=454 878) | P value |
| Total | 35.5% (35.5% to 35.6%) | 38.3% (38.1% to 38.5%) | <0.001 |
| Gender (95% CI) | |||
| Male | 39.2% (39.1% to 39.3%) | 28.5% (28.3% to 28.7%) | <0.001 |
| Female | 27.6% (27.5% to 27.7%) | 45.3% (45.1% to 45.5%) | <0.001 |
| Race (95% CI) | |||
| Non-Hispanic white | 35.4% (35.3% to 35.4%) | 34.2% (34.0% to 34.3%) | <0.001 |
| Non-Hispanic black | 18.7% (18.4% to 18.9%) | 36.4% (35.9% to 37.0%) | <0.001 |
| Hispanic | 30.9% (30.6% to 31.3%) | 0% | NA |
| Other race | 54.2% (54.0% to 54.4%) | 81.6% (81.3% to 82.0%) | <0.001 |
| Age groups (95% CI) | |||
| 40–49 years | 37.1% (37.0% to 37.3%) | 33.5% (33.1% to 33.9%) | <0.001 |
| 50–59 years | 30.0% (30.0% to 30.1%) | 50.4% (50.1% to 50.7%) | <0.001 |
| 60–69 years | 44.6% (44.5% to 44.7%) | 35.1% (34.9% to 35.3%) | <0.001 |
| 70–79 years | 29.7% (29.6% to 29.9%) | 33.8% (33.4% to 34.3%) | <0.001 |
| Smoking status (95% CI) | |||
| Current smoker | 50.7% (50.6% to 50.8%) | 43.2% (42.3% to 43.7%) | <0.001 |
| Non-smoker | 20.5% (20.4% to 20.6%) | 52.6% (52.3% to 52.9%) | <0.001 |
| Unknown smoking status | 40.6% (40.5% to 40.7%) | 30.7% (30.5% to 30.9%) | <0.001 |
| FeNO levels (ppb) (95% CI) | |||
| 0–24 | 34.6% (34.6% to 34.7%) | 27.6% (27.5% to 27.8%) | <0.001 |
| 25–50 | 30.4% (30.3% to 30.6%) | 84.4% (84.2% to 84.7%) | <0.001 |
| 51 and above | 42.3% (42.0% to 42.5%) | 0% | NA |
NA, not available.