Lung function during stable visits and PEX
| Visits | Individuals with no PEX | Visits | Individuals with at least one PEX | |
| Mean (95% CI) | Mean (95% CI) | |||
| LCI (units) | 383 | 10.47 (9.67 to 11.27) | 39 | 11.52 (8.80 to 14.25) |
| FEV1 (z-score) | 380 | −1.18 (−1.51 to −0.85) | 39 | −2.41 (−3.03 to −1.79) |
On the population level, we assessed mean (95% CI) lung function during stable visits and visits during PEX from a random-effects multilevel regression model adjusted for multiple observations and centre; 23 out of 90 individuals experienced PEX. Clinical data to define PEX were available for 422 multiple-breath washout and 419 spirometry measurements.
FEV1, forced expiratory volume in 1 s; LCI, lung clearance index; PEX, pulmonary exacerbation.