Estimated covariate effects (95% CIs) based on the model that included a linear term for age with random intercept, random slope and exponential correlation function and the model that included age using a spline with five knots, random intercept and exponential correlation function
| US | UK | |||
| Linear function | Spline | Linear function | Spline | |
| Sex=male | 1.42 (0.70, 2.14) | 1.80 (1.04, 2.55) | 2.5 (1.33, 3.7) | 2.71 (1.49, 3.93) |
| Age at diagnosis | 0.59 (0.43, 0.74) | 0.57 (0.42, 0.72) | 0.62 (0.30, 0.95) | 0.6 (0.28, 0.92) |
| Year of birth | 0.37 (0.30, 0.43) | 0.42 (0.35, 0.48) | 0.24 (0.13, 0.35) | 0.3 (0.19, 0.41) |