Table 1

Spearman correlation coefficients of radiographic and dyspnoea scores with pulmonary function, 6-minute walk distance, frailty and symptoms

DLCO (% predicted)FVC (% predicted)6MWD (m)
CT patternR2rP valueR2rP valueR2rP value
Ground glass opacities0.12−0.340.003*0.06−0.250.03*0−0.020.92
Reticulations0.41−0.64<0.001*0.04−0.210.070−0.020.8
Traction bronchiectasis0.24−0.49<0.001*0.05−0.230.04*0−0.050.69
Frailty phenotype scoreCough scaleUCSD SOBQ
CT patternR2rP valueR2rP valueR2rP value
Ground glass opacities0.210.46<0.001*00.070.560.020.140.23
Reticulations0.050.230.04*0.070.260.02*00.050.66
Traction bronchiectasis0.030.160.170.060.250.03*00.070.57
DLCO (% predicted)FVC (% predicted)6MWD (m)
R2rP valueR2rP valueR2rP value
UCSD SOBQ0.02−0.140.240.06−0.250.04*0.06−0.250.03*
Frailty phenotype scoreGrip strength (kg)Gait speed (m/s)
R2rP valueR2rP valueR2rP value
UCSD SOBQ0.220.47<0.001*0.14−0.370.001*0.05−0.210.06
  • *Significant after controlling for false discovery using the Benjamini-Hochberg method at a false discovery rate of 0.10.

  • DLCO, diffusion capacity for carbon monoxide; 6MWD, 6-minute walk distance; UCSD SOBQ, University of California San Diego Shortness of Breath Questionnaire.