Most significant differentially methylated positions (DMPs) for airway obstruction in people living with HIV
| DMP | ||||||||
| Trait | Probe | Chr** | Gene | Relation to Island | Beta | SE | P value | FDR |
| FEV1/FVC ratio <70% | cg01175605 | 2 | HK2 | Open Sea | −0.00345 | 0.032 | 4.42×10−09 | 1.16×10−03 |
| cg20868410 | 5 | HBEGF | South Shore | 0.00231 | 0.037 | 3.71×10−10 | 2.26×10−04 | |
| cg27385940 | 6 | TAPBP | Island | 0.13592 | 0.023 | 7.47×10−09 | 1.47×10−03 | |
| cg13209990 | 7 | MAD1L1 | Open Sea | −0.22058 | 0.038 | 9.65×10−09 | 1.52×10−03 | |
| cg13632595 | 19 | Unknown | Open Sea | 0.18069 | 0.320 | 5.74×10−10 | 2.26×10−04 | |
| FEV1/FVC ratio <LLN | cg13071306 | 1 | GPR153 | Island | −0.00215 | 0.029 | 5.72×10−11 | 1.50×10−05 |
| cg23455629 | 2 | Unknown | Open Sea | −0.40923 | 0.063 | 1.03×10−10 | 2.04×10−05 | |
| cg15288310 | 3 | VGLL4 | South Shelf | −0.02561 | 0.047 | 1.40×10−13 | 5.53×10−08 | |
| cg02910002 | 16 | ADCY7 | South Shelf | −0.00262 | 0.048 | 4.85×10−14 | 3.82×10−08 | |
| cg08050464 | 20 | Intergenic | South Shore | −0.27178 | 0.043 | 1.84×10−10 | 2.42×10−05 | |
*Chromosome.
FDR, false discovery rate.