Table 1

Summary of the study cohort by airflow obstruction group (FEV1/FVC<0.70 criteria)*

Status
(FEV1/FVC<0.70 criteria)
Normal lung function (n=141)Airflow obstruction (n=20)P value†
Age (years±SD)46 (43–51)49.5 (43.75–52.75)0.21
Female, %9.9950.70
Smoking status
 Current, %36.88700.01
 Former, %23.4100.25
 Never, %39.72200.14
 Pack years2 (0–15)23.75 (2.81–32.44)3.00×10−03
Race0.11
 African, %22.6910
 Asian, %0.710
 Caucasian, %59.5790
 Hispanic, %14.180
 Other, %2.840
Baseline characteristics
 BMI25.10 (23.03–28.04)22.61 (21.55–24.54)3.00×10−03
 Height, cm175.26 (170-181)178 (166.75–182.22)0.68
 Weight, kg77.7 (69.9–87.5)70 (64.23–74.55)8.00×10−03
 FEV1, mL3560 (3050–3950)2895 (2307.5–3407.5)1.51×10−03
 FEV1 %95.79 (88.25–103.38)75.18 (66.88–88.97)4.99×10−06
 FVC, mL4470 (3880–5060)4300 (3740–5127.5)0.97
 FVC %94.53 (87.87–102.73)89.34 (85.17–108.18)0.66
 FEV1/FVC ratio0.79 (0.77–0.84)0.67 (0.61–0.68)5.05×10−13
 CD4 T cells/mm3 630 (577–742)660 (589–753)0.67
 HIV RNA viral load, copies/mm3 20 250 (3851–60 798)26 100 (7710–92 300)0.33
  • *Median and IQRs.

  • †P values correspond to Mann-Whitney U test (continuous variables) and Fisher’s exact test (discrete variables).

  • BMI, body mass index.