Sensitivity analysis of the SOARS score for predicting mortality in the ISARIC validation cohort
Score cut-off | Patients N (% of total) | True positive | True negative | False positive | False negative | Sensitivity | Specificity | PPV | NPV | Cumulative mortality (%) |
>0 | 833 (5.9%) | 4284 | 799 | 9114 | 34 | 99.2% | 8.1% | 32.0% | 95.9% | 34/833 (4.1%) |
>1 | 2362 (16.6%) | 4190 | 2234 | 7679 | 128 | 97.0% | 22.5% | 35.3% | 94.6% | 128/2362 (5.4%) |
>2 | 4241 (29.8%) | 3917 | 3840 | 6073 | 401 | 90.7% | 38.7% | 39.2% | 90.5% | 401/4241 (9.5%) |
>3 | 6818 (47.9%) | 3267 | 5767 | 4146 | 1051 | 75.7% | 58.2% | 44.1% | 84.6% | 1051/6818 (15.4%) |
>4 | 10 831 (76.1%) | 1777 | 8290 | 1623 | 2541 | 41.2% | 83.6% | 52.3% | 76.5% | 2541/10 831 (23.5%) |
>5 | 13 233 (93.0%) | 607 | 9522 | 391 | 3711 | 14.1% | 96.1% | 60.8% | 72.0% | 3711/13 233 (28.0%) |
>6 | 14 172 (99.6%) | 36 | 9890 | 23 | 4282 | 0.8% | 99.8% | 61.0% | 69.8% | 4282/14 172 (30.2%) |
>7 | 14 231 (100.0%) | 0 | 9912 | 1 | 4318 | 0.0% | 100.0% | 0.0% | 69.7% | 4318/14 231 (30.3%) |
SOARS, SpO2, Obesity, Age, Respiratory rate, Stroke history.