Table 2

Metaregression to explore heterogeneity in estimate of venous thromboembolism prevalence

Studies (n)Beta (95% CI)*Intercept†P valueR2 (%)
Number of patients‡56−0.0082 (−0.0143 to −0.0021)0.19290.00811
Proportion of patients in ICU560.0017 (0.0008 to 0.0025)0.0816<0.000128
MINORS score310.0066 (−0.0065 to 0.0197)0.12120.320
D-dimers§300.0027 (0.0004 to 0.0051)0.11830.0214
Proportion of patients receiving anticoagulation380.0016 (−0.0013 to 0.0044)0.03110.290
Proportion of men400.0042 (−0.0002 to 0.0087)−0.08330.065
  • R2 estimates the amount of heterogeneity accounted for by the moderators.

  • *Beta signification: prevalence increase or decrease for the augmentation of one unit of the variable tested.

  • †Intercept signification: rate of venous thromboembolism for a variable with null value.

  • ‡Per increase of 100 patients.

  • §Per increase of 100 µg/L.

  • ICU, intensive care unit; MINORS, Methodological Index for Non-randomised Studies.