Table 1

Baseline demographic and clinical characteristics of patients with COPD included in the validation of D-PPAC and C-PPAC instruments

D-PPAC dataset
n=950
C-PPAC dataset
n=651
n*m (SD)/n (%)n*m (SD)/n (%)
Age (years)95064.5 (7.7)65167.7 (8.5)
Gender: male950597 (63)651486 (75)
Working status: employed35248 (14)64379 (12)
Current smoker950394 (41)651157 (24)
BMI (kg/m2)95027.0 (5.1)65127.3 (5.1)
Any cardiovascular disease721178 (25)593255 (43)
Diabetes95091 (10)593112 (19)
Musculoskeletal disorders720193 (27)59995 (16)
FEV1 (% predicted)94954 (17)65156 (20)
ATS/ERS stages:949651
 I—mild (FEV1 ≥80%)55 (6)80 (12)
 II—moderate (FEV1 <80% and ≥50%)489 (51)308 (47)
 III—severe (FEV1 <50% and ≥30%339 (36)202 (31)
 IV—very severe (FEV1 <30%)66 (7)61 (10)
FVC (% predicted)94996 (21)65184 (21)
FEV1/FVC (%)94948 (12)65151 (14)
6MWD (m)631446 (102)648462 (105)
Dyspnoea (mMRC 0–4)8611.6 (0.9)6501.4 (1.0)
Any COPD exacerbations last 12 m862268 (31)641323 (51)
Any COPD exacerbations requiring admissions last 12 m63366 (10)64182 (13)
CRQ dyspnoea (1-7)3045.1 (1.4)522.3 (0.7)
CRQ fatigue (1-7)3044.6 (1.2)521.7 (0.5)
CRQ emotional (1-7)3045.2 (1.1)523.4 (1.1)
CRQ mastery (1-7)3045.3 (1.3)522.0 (0.6)
CCQ symptoms (0–6)3281.9 (1.1)5971.7 (1.1)
CCQ functional (0–6)3281.8 (1.3)5971.5 (1.2)
CCQ mental (0–6)3281.4 (1.4)5971.3 (1.4)
CCQ total (0–6)3281.8 (1.0)6491.6 (1.0)
CAT (0–40)2120 (6)36513 (7)
Steps per day (n/day)9505723 (3768)6516500 (4001)
VMU/min950428 (287)651442 (320)
Time in moderate-to-vigorous physical activity (min/day)95089 (51)57498 (48)
PPAC-amount (0–100)95054 (14)65170 (16)
PPAC-difficulty (0–100)95070 (14)65178 (15)
PPAC-total (0–100)95062 (10)65174 (12)
  • *Some variables have missing values and/or are only available in some studies. Online supplemental table S4 shows patients’ characteristics stratified by study.

  • ATS/ERS, American Thoracic Society and European Respiratory Society; BMI, body mass index; CAT, chronic obstructive pulmonary disease assessment test; CCQ, clinical chronic obstructive pulmonary disease questionnaire; COPD, chronic obstructive pulmonary disease; C-PPAC, Clinical visit version of PROactive Physical Activity in COPD instrument; CRQ, chronic respiratory questionnaire; D-PPAC, Daily version of PROactive Physical Activity in COPD instrument; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; IC, inspiratory capacity; mMRC, modified medical research council dyspnoea scale; 6MWD, 6 min walking distance; PPAC, PROactive physical activity in COPD; VMU, vector magnitude unit.