Summary of the study cohort by airflow obstruction group (FEV1/FVC<0.70 criteria)*
| Status (FEV1/FVC<0.70 criteria) | Normal lung function (n=141) | Airflow obstruction (n=20) | P value† |
| Age (years±SD) | 46 (43–51) | 49.5 (43.75–52.75) | 0.21 |
| Female, % | 9.99 | 5 | 0.70 |
| Smoking status | |||
| Current, % | 36.88 | 70 | 0.01 |
| Former, % | 23.4 | 10 | 0.25 |
| Never, % | 39.72 | 20 | 0.14 |
| Pack years | 2 (0–15) | 23.75 (2.81–32.44) | 3.00×10−03 |
| Race | 0.11 | ||
| African, % | 22.69 | 10 | |
| Asian, % | 0.71 | 0 | |
| Caucasian, % | 59.57 | 90 | |
| Hispanic, % | 14.18 | 0 | |
| Other, % | 2.84 | 0 | |
| Baseline characteristics | |||
| BMI | 25.10 (23.03–28.04) | 22.61 (21.55–24.54) | 3.00×10−03 |
| Height, cm | 175.26 (170-181) | 178 (166.75–182.22) | 0.68 |
| Weight, kg | 77.7 (69.9–87.5) | 70 (64.23–74.55) | 8.00×10−03 |
| FEV1, mL | 3560 (3050–3950) | 2895 (2307.5–3407.5) | 1.51×10−03 |
| FEV1 % | 95.79 (88.25–103.38) | 75.18 (66.88–88.97) | 4.99×10−06 |
| FVC, mL | 4470 (3880–5060) | 4300 (3740–5127.5) | 0.97 |
| FVC % | 94.53 (87.87–102.73) | 89.34 (85.17–108.18) | 0.66 |
| FEV1/FVC ratio | 0.79 (0.77–0.84) | 0.67 (0.61–0.68) | 5.05×10−13 |
| CD4 T cells/mm3 | 630 (577–742) | 660 (589–753) | 0.67 |
| HIV RNA viral load, copies/mm3 | 20 250 (3851–60 798) | 26 100 (7710–92 300) | 0.33 |
*Median and IQRs.
†P values correspond to Mann-Whitney U test (continuous variables) and Fisher’s exact test (discrete variables).
BMI, body mass index.