Table 1

Descriptive statistics of subjects with information on gran-maternal smoking during pregnancy (maternal and/or paternal) stratified by age-group: children (>4 year and <18 year) and adults (≥18 year and ≤50 year)

ChildrenAdultsP value
N11 54425 747
Age, years10.5 (3.7)31.0 (8.4)<0.001
Male gender5638 (48.8)9829 (38.2)<0.001
Grandmaternal smoking
 Maternal2501 (24.4)1410 (6.6)<0.001
 Paternal1374 (18.8)686 (4.8)<0.001
Maternal smoking1226 (11.5)4755 (20.8)<0.001
Asthma1214 (11.4)2805 (11.0)0.316
Early childhood asthma967 (9.3)1054 (4.4)<0.001
Spirometry performed7058 (61.1)17 901 (69.5)<0.001
FEV1 % predicted95.2 (10.4)95.2 (11.1)0.732
FVC % predicted96.3 (10.0)98.6 (10.6)<0.001
FEV1/FVC0.86 (0.06)0.80 (0.07)<0.001
FEV1/FVC % predicted98.2 (7.1)96.0 (7.2)<0.001
Active smoking
 Never10 909 (95.7)14 322 (58.7)
 Ex98 (0.9)4463 (18.3)<0.001
 Current391 (3.4)5616 (23.0)
ETS in childhood
 No7600 (71.0)9831 (39.7)
 Yes2045 (19.1)14 785 (59.7)<0.001
 Unknown1056 (9.9)148 (0.6)
Maternal age, years29.8 (4.1)26.9 (4.1)<0.001
Birth weight, g3499.1 (616.0)3434.7 (580.9)<0.001
Gestational age, years39.6 (2.0)39.8 (1.8)<0.001
Breast feeding
 No1967 (18.5)6157 (25.0)
 Yes8677 (81.4)17 485 (71.0)<0.001
 Unknown10 (0.1)977 (4.0)
Income
 <1000167 (1.4)4755 (18.5)
 1000–20001317 (11.4)5297 (20.6)
 2000–30003763 (32.6)6204 (24.1)<0.001
 >30005286 (45.8)6708 (26.1)
 other1004 (8.7)2781 (10.8)
Education
 Low406 (3.5)1613 (6.3)
 Intermediate5579 (48.4)14 359 (55.8)<0.001
 High5499 (47.7)9437 (36.7)
 Other/unknown54 (0.5)336 (1.3)
  • ETS, environmental tobacco smoke.